Klebsiella pneumoniae strain FDAARGOS_775

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain FDAARGOS_775 is a pathogenic, Gram-negative bacterium characterized as a facultative anaerobe and a chemoheterotroph, thriving optimally at 37°C. This mesophilic organism typically exists in various arrangements, including chains, pairs, and singles, and possesses flagella, indicating mobility. The bacterium is nonsporulating and has a complex genomic structure consisting of three replicons. K. pneumoniae is known to have a wide range of hosts, including Homo sapiens, Gallus gallus, and other vertebrates such as Danio rerio and Ovis aries, as well as various invertebrates and plants. This diverse host range highlights its ecological versatility and ability to adapt to different environments. Clinically, K. pneumoniae strain FDAARGOS_775 is associated with numerous health issues, including bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. The strain can also lead to severe conditions such as sepsis, neonatal sepsis, and various abscesses, demonstrating its significant pathogenic potential in humans. The strain's free-living characteristics suggest that it may thrive in both host-associated and environmental niches, emphasizing its ecological role. Given its pathogenicity, understanding the behavior and transmission of K. pneumoniae strain FDAARGOS_775 is crucial for managing infections and informing public health strategies. This bacterium exemplifies the complex interplay between microbial life and its hosts, underscoring the importance of continued research into its biology and ecology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain FDAARGOS_775

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain FDAARGOS_775
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain FDAARGOS_775


Gene Summary

Adenine Count

1132236 bp

Thymine Count

1127353 bp

Guanine Count

1520260 bp

Cytosine Count

1523186 bp

Genome Length

5303035 bp

Protein-coding Genes

4894 genes

Non-Coding Genes

223 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Minor tail proteinFIU12_RS16495Not AvailablePositive3361231 - 336198628053.8
Minor tail proteinFIU12_RS16500Not AvailablePositive3361988 - 336269827637.7
Putative lipoproteinFIU12_RS28840Not AvailablePositive3362891 - 33631429425.38
Tail assembly protein iFIU12_RS16510Not AvailablePositive3363189 - 336378220684.5
Gp21FIU12_RS16515Not AvailablePositive3363845 - 3376549450711.0
Tail fibers proteinFIU12_RS16520Not AvailablePositive3376618 - 337811453313.9
AttrNot AvailableNot AvailablePositive3389144 - 3389156Not Available
AttlNot AvailableNot AvailablePositive5126425 - 5126436Not Available
Anaerobic sulfatase-maturating enzymeFIU12_RS25040Not AvailablePositive5138597 - 513977544187.8
sulfatase-like hydrolase/transferaseFIU12_RS25045Not AvailablePositive5139759 - 514162771272.5

Displaying genes 71 – 80 of 5268 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total