Escherichia coli strain FC853_EC

Escherichia coli strain FC853_EC is a Gram-negative, rod-shaped bacterium that typically lives in host-associated environments. It exhibits a cell arrangement of singles and pairs, and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic conditions. This strain is motile and possesses flagella, which may assist in its movement within various hosts. The optimal growth temperature for FC853_EC is 37°C, placing it within the mesophilic temperature range, which is conducive to its survival in warm-blooded hosts, including humans (Homo sapiens) and a variety of other animals such as Gallus gallus (chickens), Bos taurus (cattle), and Canis lupus familiaris (domestic dogs). It has been observed in numerous hosts across multiple taxa, indicating its wide ecological niche. FC853_EC is associated with a range of health effects, particularly in humans, where it is known to cause urinary tract infections (UTIs), gastrointestinal infections, and serious conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's pathogenicity highlights its potential to cause significant health issues, particularly in vulnerable populations like neonates. With five replicons and two membranes, FC853_EC's genetic and structural characteristics support its adaptability and pathogenic potential. Given its diverse range of hosts and associated health risks, FC853_EC plays a notable role in public health, particularly concerning foodborne infections and the transmission of antibiotic resistance within microbial communities.