Enterococcus faecalis strain HA-1

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecalis strain HA-1 is a Gram-positive, cocci-shaped bacterium that functions as a facultative anaerobe and is classified as a chemoorganotroph. It has a mesophilic temperature range, with an optimal growth temperature of 37°C. The strain is non-motile and does not possess flagella, and it contains two replicons and a single membrane. This strain exhibits a free-living biotic relationship and is found in multiple habitats. It has been identified as a pathogen in humans and is associated with a variety of health effects, including bacteremia, urinary tract infections (UTIs), endocarditis, meningitis, and septicemia. It can cause infections in various body parts, such as the urinary tract, intra-abdomen, pelvic regions, surgical sites, and the oral cavity. Additionally, it is implicated in nosocomial infections and can lead to serious conditions like infectious lesions and interstitial pneumonia. E. faecalis strain HA-1 has a diverse host range, affecting not only Homo sapiens but also species including Gallus gallus, Bos, various Metazoa, and several aquatic and terrestrial animals. This wide host range underscores its ecological versatility and potential for cross-species transmission. The strain’s pathogenicity and ability to thrive in different environments highlight its significance in both healthcare settings and ecological interactions.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecalis
Strainstrain HA-1

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Enterococcus faecalis strain HA-1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Enterococcus faecalis strain HA-1 chromosome, complete genome.

Gene Summary

Adenine Count

901809 bp

Thymine Count

900125 bp

Guanine Count

537053 bp

Cytosine Count

542094 bp

Genome Length

2881081 bp

Protein-coding Genes

2615 genes

Non-Coding Genes

187 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf896 domain-containing proteinFHO10_RS00530Not AvailablePositive24149 - 243738833.52
peptide abc transporter substrate-binding proteinFHO10_RS00535Not AvailableNegative24420 - 2609961479.9
5'-nucleotidase c-terminal domain-containing proteinFHO10_RS00540Not AvailableNegative26235 - 30368150388.0
bifunctional udp-n-acetylglucosamine diphosphorylase/glucosamine-1-phosphate n-acetyltransferase glmuFHO10_RS00545Not AvailableNegative30809 - 3218549490.8
pur operon repressorFHO10_RS00550Not AvailableNegative32396 - 3321730476.8
metal abc transporter permeaseFHO10_RS00555Not AvailableNegative33361 - 3420030639.3
metal abc transporter atp-binding proteinFHO10_RS00560Not AvailableNegative34363 - 3505526477.6
metal abc transporter substrate-binding proteinFHO10_RS00565Not AvailableNegative35081 - 3603435199.6
4-(cytidine 5'-diphospho)-2-c-methyl-d-erythritol kinaseFHO10_RS00575Not AvailableNegative36201 - 3705231282.9
veg family proteinFHO10_RS00580Not AvailableNegative37233 - 3753511414.8

Displaying genes 161 – 170 of 2885 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
EndophthalmitisCausesPMC10638747
Refractory apical periodontitisCausesPMC11307051
Infections in various body parts such as urinary tract, intra-abdomen and pelvic regions, surgical sites and oral cavityCausesPMC11307051
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Urinary tract infectionsCausesPMC11784074
MastitisCausesPMC13343983
PyelonephritisCausesPMC4308012
Various infectionsCausesPMC5109407
MeningitisCausesPMC5109407

Displaying health effects 1 – 10 of 47 in total