Staphylococcus epidermidis strain HD43

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus epidermidis strain HD43 is a Gram-positive cocci bacterium that typically exists in clusters or singles. It is a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments, and thrives optimally at a temperature of 30°C, falling within the mesophilic temperature range. This strain is non-motile, indicating the absence of flagella, and possesses one membrane and one replicon. S. epidermidis strain HD43 is associated with various hosts, including Homo sapiens (humans), Bos taurus (cattle), Phocidae (seals), and Equidae (horses). It exhibits a free-living biotic relationship, highlighting its ecological versatility. Despite its presence in diverse habitats, this bacterium is known to cause several health issues, particularly in humans. It has been implicated in urinary tract infections (UTIs), peritonitis, bloodstream infections, late-onset sepsis, pyelonephritis, prosthetic valve endocarditis, central venous catheter infections, cerebrospinal fluid shunt meningitis, acute bacterial meningitis, and infections related to implanted cardiac devices. These infections are often associated with biomaterials, suggesting that S. epidermidis can act as a pathogen in clinical settings, particularly when medical devices are involved. Understanding the pathogenic potential of S. epidermidis strain HD43 is crucial, especially in hospital environments where its presence on biomaterials can lead to serious health complications. The ability of this strain to inhabit diverse hosts and cause a range of infections underscores its significance in both microbiology and clinical medicine.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus epidermidis
Strainstrain HD43

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus epidermidis strain HD43
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Bos taurus, Ovis aries
Cell arrangementClusters - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Staphylococcus epidermidis strain HD43 chromosome.

Gene Summary

Adenine Count

835113 bp

Thymine Count

811611 bp

Guanine Count

391117 bp

Cytosine Count

384349 bp

Genome Length

2424890 bp

Protein-coding Genes

2222 genes

Non-Coding Genes

87 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
diaminopimelate decarboxylaseFH487_RS06810Not AvailableNegative1394156 - 139542146620.4
alanine racemaseFH487_RS06815Not AvailableNegative1395422 - 139649541601.4
amidohydrolaseFH487_RS06820Not AvailableNegative1396501 - 139765243649.7
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n-acetyltransferaseFH487_RS06825Not AvailableNegative1397809 - 139853125488.7
4-hydroxy-tetrahydrodipicolinate reductaseFH487_RS06830Not AvailableNegative1398553 - 139927526751.9
4-hydroxy-tetrahydrodipicolinate synthaseFH487_RS06835Not AvailableNegative1399275 - 140015933133.3
aspartate-semialdehyde dehydrogenaseFH487_RS06840Not AvailableNegative1400161 - 140115036339.1
aspartate kinaseFH487_RS06845Not AvailableNegative1401221 - 140245344988.0
abc-f family atp-binding cassette domain-containing proteinFH487_RS06850Not AvailableNegative1403032 - 140463960518.7
rna-binding virulence regulatory protein cvfbFH487_RS06855Not AvailablePositive1404850 - 140574633988.2

Displaying genes 1341 – 1350 of 2309 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PyelonephritisCausesPMC4308012
Prosthetic valve endocarditisCausesPMC4308012
Central venous catheter infectionsCausesPMC4308012
Cerebrospinal fluid shunt meningitisCausesPMC4308012
UtiCausesPMC4308012
Late-onset sepsisCausesPMC4601917
Infections of implanted cardiac devicesCausesPMC6060398
Acute bacterial meningitisCausesPMC6306750
Bloodstream infectionsCausesPMC8471643
PeritonitisCausesPMC7747055

Displaying health effects 1 – 10 of 11 in total