Staphylococcus epidermidis strain HD43

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus epidermidis strain HD43 is a Gram-positive cocci bacterium that typically exists in clusters or singles. It is a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments, and thrives optimally at a temperature of 30°C, falling within the mesophilic temperature range. This strain is non-motile, indicating the absence of flagella, and possesses one membrane and one replicon. S. epidermidis strain HD43 is associated with various hosts, including Homo sapiens (humans), Bos taurus (cattle), Phocidae (seals), and Equidae (horses). It exhibits a free-living biotic relationship, highlighting its ecological versatility. Despite its presence in diverse habitats, this bacterium is known to cause several health issues, particularly in humans. It has been implicated in urinary tract infections (UTIs), peritonitis, bloodstream infections, late-onset sepsis, pyelonephritis, prosthetic valve endocarditis, central venous catheter infections, cerebrospinal fluid shunt meningitis, acute bacterial meningitis, and infections related to implanted cardiac devices. These infections are often associated with biomaterials, suggesting that S. epidermidis can act as a pathogen in clinical settings, particularly when medical devices are involved. Understanding the pathogenic potential of S. epidermidis strain HD43 is crucial, especially in hospital environments where its presence on biomaterials can lead to serious health complications. The ability of this strain to inhabit diverse hosts and cause a range of infections underscores its significance in both microbiology and clinical medicine.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus epidermidis
Strainstrain HD43

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus epidermidis strain HD43
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Bos taurus, Ovis aries
Cell arrangementClusters - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Staphylococcus epidermidis strain HD43 chromosome.

Gene Summary

Adenine Count

835113 bp

Thymine Count

811611 bp

Guanine Count

391117 bp

Cytosine Count

384349 bp

Genome Length

2424890 bp

Protein-coding Genes

2222 genes

Non-Coding Genes

87 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
5-formyltetrahydrofolate cyclo-ligaseFH487_RS06070Not AvailablePositive1229522 - 123007321333.6
rhomboid family proteinFH487_RS06075Not AvailablePositive1230074 - 123153457029.1
yqgq family proteinFH487_RS06080Not AvailablePositive1231518 - 12317188170.1
rok family glucokinaseFH487_RS06085Not AvailablePositive1231718 - 123270435046.7
mth1187 family thiamine-binding proteinFH487_RS06090Not AvailablePositive1232704 - 123303012320.9
mbl fold metallo-hydrolaseFH487_RS06095Not AvailablePositive1233030 - 123365323172.4
competence type iv pilus atpase comgaFH487_RS06100Not AvailablePositive1233710 - 123468437332.6
competence type iv pilus assembly protein comgbFH487_RS06105Not AvailablePositive1234656 - 123572342382.2
competence type iv pilus major pilin comgcFH487_RS06110Not AvailablePositive1235741 - 123605811492.3
competence type iv pilus minor pilin comgdFH487_RS06115Not AvailablePositive1236048 - 123648517061.9

Displaying genes 1201 – 1210 of 2309 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PyelonephritisCausesPMC4308012
Prosthetic valve endocarditisCausesPMC4308012
Central venous catheter infectionsCausesPMC4308012
Cerebrospinal fluid shunt meningitisCausesPMC4308012
UtiCausesPMC4308012
Late-onset sepsisCausesPMC4601917
Infections of implanted cardiac devicesCausesPMC6060398
Acute bacterial meningitisCausesPMC6306750
Bloodstream infectionsCausesPMC8471643
PeritonitisCausesPMC7747055

Displaying health effects 1 – 10 of 11 in total