Enterobacter cloacae strain NH77

Enterobacter cloacae strain NH77 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain possesses a single replicon and features two membranes, which is characteristic of its Gram-negative classification. Notably, Enterobacter cloacae NH77 does not exhibit mobility, despite the presence of flagella. This bacterium is mesophilic, meaning it prefers moderate temperature ranges for optimal growth. It is free-living and has been identified in multiple habitats, indicating its environmental versatility. Enterobacter cloacae strain NH77 has been associated with various hosts, including Homo sapiens (humans), Bos (cattle), and Okapia johnstoni (okapi), reflecting its potential to inhabit diverse biological systems. Clinically, Enterobacter cloacae strain NH77 is significant due to its pathogenicity in humans. It is linked to several health issues, including vertebral osteomyelitis, bacteremia, spondylodiscitis, and various bloodstream infections (BSI), as well as urinary and respiratory tract infections. These associations highlight the bacterium's role as an opportunistic pathogen, particularly in immunocompromised individuals. From an ecological perspective, the presence of Enterobacter cloacae strain NH77 in multiple hosts and its ability to cause disease underscore the importance of monitoring and understanding this bacterium in both clinical and environmental contexts. Its adaptability and pathogenic potential warrant further investigation to mitigate its health impacts on humans and other animals.