Klebsiella pneumoniae strain KpvST147B_SE1_1_NDM

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain KpvST147B_SE1_1_NDM is a Gram-negative, rod-shaped bacterium that demonstrates a versatile lifestyle as a facultative anaerobe and chemoheterotroph. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically exhibits a cell arrangement consisting of chains, pairs, and singles. KpvST147B_SE1_1_NDM thrives optimally at 37°C, aligning with mesophilic organisms. It has a complex genomic structure, comprising four replicons and two membranes, which may contribute to its adaptability in various environments. This strain is primarily associated with hosts including Homo sapiens and various animal species such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (domestic dogs), indicating its potential as a zoonotic pathogen. The health effects attributed to KpvST147B_SE1_1_NDM are significant, including a range of serious infections such as bacteremia, urinary tract infections, pneumonia, and sepsis. Its pathogenicity in humans is notable, as it can cause severe complications like liver abscesses and meningitis. Given its capacity to infect a diverse array of hosts and its association with serious health risks, KpvST147B_SE1_1_NDM exemplifies the challenges posed by opportunistic pathogens in both clinical and ecological contexts. Its presence in multiple hosts underscores the importance of monitoring and controlling the spread of this strain to mitigate public health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain KpvST147B_SE1_1_NDM

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain KpvST147B_SE1_1_NDM
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain KpvST147B_SE1_1_NDM


Gene Summary

Adenine Count

27265 bp

Thymine Count

30267 bp

Guanine Count

26706 bp

Cytosine Count

28469 bp

Genome Length

112707 bp

Protein-coding Genes

55 genes

Non-Coding Genes

64 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinFGF03_RS29565Not AvailableNegative45587 - 4588611359.0
Hypothetical proteinFGF03_RS29570Not AvailableNegative45883 - 460355607.12
Putative dna ligaseFGF03_RS31680Not AvailableNegative46053 - 461664196.36
Hypothetical proteinFGF03_RS29575Not AvailableNegative46166 - 4663317132.5
Hypothetical proteinFGF03_RS29580Not AvailableNegative46713 - 4750128778.6
hypothetical proteinFGF03_RS29585Not AvailablePositive47790 - 4895645320.7
Putative dna primaseFGF03_RS29590Not AvailableNegative48991 - 5011542223.7
Putative dna helicaseFGF03_RS29595Not AvailableNegative50262 - 5160249925.6
Hypothetical proteinFGF03_RS29600Not AvailableNegative51667 - 5239228761.3
Hypothetical proteinFGF03_RS29605Not AvailablePositive52686 - 5374441074.4

Displaying genes 11 – 20 of 338 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total