Escherichia coli strain A1_181

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain A1_181 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. This strain exhibits mobility, facilitated by the presence of flagella, and typically arranges itself in pairs or as single cells. It is mesophilic, with an optimal growth temperature of 37°C. A1_181 is host-associated and demonstrates a free-living biotic relationship. It has a diverse range of hosts, including Homo sapiens (humans), various livestock such as Bos taurus (cattle) and Sus scrofa (pigs), as well as a variety of vertebrates and even some plants like Solanum lycopersicum (tomato). This broad host range suggests its ecological versatility and potential for transmission across different species. Health effects associated with E. coli strain A1_181 include a significant number of clinical conditions, particularly urinary tract infections (UTIs), gastrointestinal infections, and more severe complications such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's pathogenicity in humans highlights its potential as a serious public health concern, particularly in foodborne infections. The ecological insight drawn from the traits of E. coli strain A1_181 underscores its role in both environmental and clinical settings. Its ability to infect a wide array of hosts, coupled with its pathogenic potential, emphasizes the importance of monitoring and managing this strain to mitigate health risks associated with its transmission and persistence in various habitats.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain A1_181

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain A1_181
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain A1_181 plasmid p_unnamed2, complete

Gene Summary

Adenine Count

25514 bp

Thymine Count

25282 bp

Guanine Count

23206 bp

Cytosine Count

23580 bp

Genome Length

97582 bp

Protein-coding Genes

5 genes

Non-Coding Genes

109 genes

# of Chromosomes/Plasmids

6

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenaseFDP43_RS06755Not AvailableNegative1353381 - 135419328471.3
bifunctional 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunitFDP43_RS06760Not AvailableNegative1354190 - 135451011329.3
3-phenylpropionate/cinnamic acid dioxygenase subunit betaFDP43_RS06765Not AvailableNegative1354510 - 135502820580.3
3-phenylpropionate/cinnamic acid dioxygenase subunit alphaFDP43_RS06770Not AvailableNegative1355025 - 135638651111.8
dna-binding transcriptional regulator hcarFDP43_RS06775Not AvailablePositive1356522 - 135741232840.2
3-phenylpropionate mfs transporterFDP43_RS06780Not AvailablePositive1357572 - 135871141595.1
stationary phase inducible protein csieFDP43_RS06785Not AvailableNegative1358703 - 135998349043.4
alpha/beta hydrolaseFDP43_RS06790Not AvailableNegative1360174 - 136102831445.6
inositol-1-monophosphataseFDP43_RS06795Not AvailableNegative1361173 - 136197629173.8
trna (cytosine(32)/uridine(32)-2'-o)-methyltransferase trmjFDP43_RS06800Not AvailablePositive1362095 - 136283226920.4

Displaying genes 1731 – 1740 of 4884 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total