Escherichia coli strain A1_181

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain A1_181 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. This strain exhibits mobility, facilitated by the presence of flagella, and typically arranges itself in pairs or as single cells. It is mesophilic, with an optimal growth temperature of 37°C. A1_181 is host-associated and demonstrates a free-living biotic relationship. It has a diverse range of hosts, including Homo sapiens (humans), various livestock such as Bos taurus (cattle) and Sus scrofa (pigs), as well as a variety of vertebrates and even some plants like Solanum lycopersicum (tomato). This broad host range suggests its ecological versatility and potential for transmission across different species. Health effects associated with E. coli strain A1_181 include a significant number of clinical conditions, particularly urinary tract infections (UTIs), gastrointestinal infections, and more severe complications such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's pathogenicity in humans highlights its potential as a serious public health concern, particularly in foodborne infections. The ecological insight drawn from the traits of E. coli strain A1_181 underscores its role in both environmental and clinical settings. Its ability to infect a wide array of hosts, coupled with its pathogenic potential, emphasizes the importance of monitoring and managing this strain to mitigate health risks associated with its transmission and persistence in various habitats.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain A1_181

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain A1_181
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain A1_181 plasmid p_unnamed2, complete

Gene Summary

Adenine Count

25514 bp

Thymine Count

25282 bp

Guanine Count

23206 bp

Cytosine Count

23580 bp

Genome Length

97582 bp

Protein-coding Genes

5 genes

Non-Coding Genes

109 genes

# of Chromosomes/Plasmids

6

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fad-binding oxidoreductaseFDP43_RS05695Not AvailablePositive1141117 - 114257153698.4
mfs transporterFDP43_RS05700Not AvailablePositive1142593 - 114400250862.3
electron transfer flavoprotein subunit beta/fixa family proteinFDP43_RS05705Not AvailablePositive1143980 - 114475928750.1
electron transfer flavoprotein subunit alpha/fixb family proteinFDP43_RS05710Not AvailablePositive1144756 - 114561630308.4
glycerol-3-phosphate responsive antiterminatorFDP43_RS05715Not AvailableNegative1145764 - 114633920787.6
ferredoxin family proteinFDP43_RS05720Not AvailableNegative1146356 - 11466169636.47
fad-dependent oxidoreductaseFDP43_RS05725Not AvailableNegative1146607 - 114787846215.6
6-carboxytetrahydropterin synthase quedFDP43_RS05730Not AvailableNegative1147956 - 114831813642.4
nadph-dependent assimilatory sulfite reductase flavoprotein subunitFDP43_RS05735Not AvailablePositive1148637 - 115043666283.4
assimilatory sulfite reductase (nadph) hemoprotein subunitFDP43_RS05740Not AvailablePositive1150436 - 115214863963.8

Displaying genes 1521 – 1530 of 4884 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total