Acinetobacter baumannii strain ACN21

Gram-negativeRodNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Moraxellales

Family

Moraxellaceae

Genus

Acinetobacter

Description

Acinetobacter baumannii strain ACN21 is a Gram-negative, rod-shaped bacterium that exhibits characteristics of a heterotrophic chemoheterotroph. This organism is an aerobic species, requiring oxygen for growth, and is mesophilic, with an optimal growth temperature of 37°C. It is characterized by a lack of mobility, although it possesses flagella. This strain has a complex genetic structure, consisting of nine replicons and two membranes, and is classified as free-living. It has been isolated from multiple habitats and is known to interact with various hosts, including humans (Homo sapiens), chickens (Gallus gallus), and cattle (Bos taurus). Acinetobacter baumannii strain ACN21 is notable for its pathogenic potential, being associated with a range of serious health effects in humans. These include bacteremia, necrotizing fasciitis, bloodstream infections, urinary tract infections, nosocomial infections, hospital-acquired pneumonia, traumatic injuries, respiratory tract infections, healthcare-associated infections, severe infections, and wound contaminations. It is also implicated in community-acquired infections. The ecological persistence of A. baumannii in various environments contributes to its role as a significant opportunistic pathogen. Its ability to thrive in diverse habitats and its resistance to many antimicrobial agents highlight the challenges of managing infections caused by this organism, particularly in healthcare settings where it is often encountered. The presence of multiple genetic accessions further suggests genetic diversity within the strain, which may influence its pathogenicity and environmental adaptability.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderMoraxellales
FamilyMoraxellaceae
GenusAcinetobacter
SpeciesAcinetobacter baumannii
Strainstrain ACN21

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Acinetobacter baumannii strain ACN21
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementSingles
SporulationNot Available
Energy sourceHeterotroph - Chemoheterotroph
PathogenicityHuman

Gene Summary

Adenine Count

31794 bp

Thymine Count

35946 bp

Guanine Count

23552 bp

Cytosine Count

24755 bp

Genome Length

116047 bp

Protein-coding Genes

59 genes

Non-Coding Genes

70 genes

# of Chromosomes/Plasmids

9

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
2,3-butanediol dehydrogenaseE5D09_RS01000Not AvailableNegative217362 - 21842037706.6
acetoin reductaseE5D09_RS01005Not AvailableNegative218450 - 21923527635.1
dihydrolipoyl dehydrogenaseE5D09_RS01010Not AvailableNegative219262 - 22066549856.2
2-oxo acid dehydrogenase subunit e2E5D09_RS01015Not AvailableNegative220676 - 22220254254.0
alpha-ketoacid dehydrogenase subunit betaE5D09_RS01020Not AvailableNegative222204 - 22322336593.0
thiamine pyrophosphate-dependent dehydrogenase e1 component subunit alphaE5D09_RS01025Not AvailableNegative223237 - 22419934404.9
lipoyl synthaseE5D09_RS01030Not AvailablePositive224564 - 22555037440.3
helix-turn-helix domain-containing proteinE5D09_RS01035Not AvailablePositive225708 - 22684742868.3
tena family transcriptional regulatorE5D09_RS01040Not AvailableNegative226894 - 22764628918.2
eal domain-containing proteinE5D09_RS01045Not AvailablePositive227967 - 22919646361.2

Displaying genes 501 – 510 of 3899 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Hospital-acquired pneumoniaCausesPMC11264759
BacteremiaCausesPMC11264759
Urinary tract infectionsCausesPMC11264759
Traumatic injuriesCausesPMC11264759
Respiratory tract infectionCausesPMC11514839
Healthcare-associated infectionsCausesPMC13168211
BacteremiaCausesPMC10561989
Hospital-acquired pneumoniaCausesPMC11925754
Bloodstream infectionsCausesPMC11925754
Wound contaminationsCausesPMC11925754

Displaying health effects 1 – 10 of 14 in total