Escherichia coli strain CFSAN027346

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain CFSAN027346 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It typically resides in host-associated habitats and is mesophilic, with an optimal growth temperature of 37°C. CFSAN027346 has a complex biotic relationship, being free-living and associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), various mammals, birds, and even some plant species such as Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). This strain is known for its pathogenicity in humans, associated with various health effects. It can cause urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and more severe conditions such as septicemia and hemolytic uremic syndrome (HUS). The range of diseases linked to CFSAN027346 underscores its impact on both human health and animal health, as it can also lead to conditions like colibacillosis in livestock. The presence of this strain in diverse hosts reflects its ecological versatility and ability to adapt to different environments, potentially contributing to the transmission of pathogenic traits across species. This adaptability may facilitate the persistence of pathogenic E. coli in various ecosystems, highlighting the importance of monitoring and understanding such strains in public health and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain CFSAN027346

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain CFSAN027346
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain CFSAN027346 plasmid pCFSAN027346-1,

Gene Summary

Adenine Count

24934 bp

Thymine Count

25270 bp

Guanine Count

23058 bp

Cytosine Count

22754 bp

Genome Length

96016 bp

Protein-coding Genes

101 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
invasion regulator sirb1EKI52_RS02220Not AvailableNegative425339 - 42614830871.1
invasion regulator sirb2EKI52_RS02225Not AvailableNegative426152 - 42654414625.7
peptide chain release factor n(5)-glutamine methyltransferaseEKI52_RS02230Not AvailableNegative426541 - 42737430976.8
peptide chain release factor 1EKI52_RS02235Not AvailableNegative427374 - 42845640519.6
glutamyl-trna reductaseEKI52_RS02240Not AvailableNegative428498 - 42975446332.5
lipoprotein insertase outer membrane protein lolbEKI52_RS02245Not AvailablePositive429968 - 43059123552.1
4-(cytidine 5'-diphospho)-2-c-methyl-d-erythritol kinaseEKI52_RS02250Not AvailablePositive430591 - 43144230971.2
ribose-phosphate diphosphokinaseEKI52_RS02255Not AvailablePositive431593 - 43254034220.3
c4-dicarboxylic acid transporter dauaEKI52_RS02260Not AvailablePositive432692 - 43434458388.5
stress-induced protein ychhEKI52_RS02265Not AvailableNegative434399 - 43467710486.9

Displaying genes 1471 – 1480 of 5845 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total