Bacteroides fragilis strain DCMOUH0085B

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain DCMOUH0085B is a Gram-negative, mesophilic anaerobic bacterium characterized by its rod shape and the presence of flagella. It is classified as a chemoorganotroph, utilizing organic compounds as its energy source. This strain typically lives in association with hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes, indicating a versatile ecological niche. The bacterium is known to exist as singles, rather than in clusters, and has a single replicon and a double membrane structure. Its optimal growth temperature is 37°C, aligning with the typical human body temperature, which may facilitate its pathogenic interactions. Bacteroides fragilis is associated with a range of health implications, particularly in humans, where it can lead to serious conditions such as bacteremia, abscesses, and various gastrointestinal diseases, including diarrhea, colitis, and colorectal cancer. Its pathogenicity is underscored by its capacity to cause anaerobic bacteremia and intraabdominal abscesses, contributing to local tissue infections and septicemia. The ecological role of Bacteroides fragilis strain DCMOUH0085B highlights its dual nature as a free-living organism that can thrive in the human microbiome, while also posing significant health risks. This duality illustrates the complex interactions between host-associated microbes and their potential to influence both health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain DCMOUH0085B

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain DCMOUH0085B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain DCMOUH0085B chromosome, complete

Gene Summary

Adenine Count

1549643 bp

Thymine Count

1554580 bp

Guanine Count

1194780 bp

Cytosine Count

1205073 bp

Genome Length

5504076 bp

Protein-coding Genes

4471 genes

Non-Coding Genes

121 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphate abc transporter atp-binding protein pstbIB64_RS18080Not AvailableNegative4218816 - 421957728497.3
phosphate abc transporter permease pstaIB64_RS18085Not AvailableNegative4219599 - 422047431561.8
phosphate abc transporter permease subunit pstcIB64_RS18090Not AvailableNegative4220476 - 422167243294.6
psts family phosphate abc transporter substrate-binding proteinIB64_RS18095Not AvailablePositive4221959 - 422277129635.7
glutamine--trna ligase/yqey domain fusion proteinIB64_RS18100Not AvailablePositive4222842 - 422458166574.9
lipopolysaccharide assembly protein lapbIB64_RS18105Not AvailablePositive4224770 - 422620654370.7
deda family proteinIB64_RS18110Not AvailablePositive4226338 - 422697923906.5
duf4840 domain-containing proteinIB64_RS18120Not AvailablePositive4227361 - 422798422452.8
thiol peroxidaseIB64_RS18125Not AvailableNegative4228069 - 422856917954.8
hded family acid-resistance proteinIB64_RS18130Not AvailablePositive4228662 - 422924322011.8

Displaying genes 3551 – 3560 of 4592 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total