Bacteroides fragilis strain DCMOUH0085B

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain DCMOUH0085B is a Gram-negative, mesophilic anaerobic bacterium characterized by its rod shape and the presence of flagella. It is classified as a chemoorganotroph, utilizing organic compounds as its energy source. This strain typically lives in association with hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes, indicating a versatile ecological niche. The bacterium is known to exist as singles, rather than in clusters, and has a single replicon and a double membrane structure. Its optimal growth temperature is 37°C, aligning with the typical human body temperature, which may facilitate its pathogenic interactions. Bacteroides fragilis is associated with a range of health implications, particularly in humans, where it can lead to serious conditions such as bacteremia, abscesses, and various gastrointestinal diseases, including diarrhea, colitis, and colorectal cancer. Its pathogenicity is underscored by its capacity to cause anaerobic bacteremia and intraabdominal abscesses, contributing to local tissue infections and septicemia. The ecological role of Bacteroides fragilis strain DCMOUH0085B highlights its dual nature as a free-living organism that can thrive in the human microbiome, while also posing significant health risks. This duality illustrates the complex interactions between host-associated microbes and their potential to influence both health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain DCMOUH0085B

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain DCMOUH0085B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain DCMOUH0085B chromosome, complete

Gene Summary

Adenine Count

1549643 bp

Thymine Count

1554580 bp

Guanine Count

1194780 bp

Cytosine Count

1205073 bp

Genome Length

5504076 bp

Protein-coding Genes

4471 genes

Non-Coding Genes

121 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nucleoid-associated proteinIB64_RS13410Not AvailablePositive3168256 - 316929640280.3
rna-binding domain-containing proteinIB64_RS13415Not AvailablePositive3169301 - 317080056979.4
site-specific integraseIB64_RS13425Not AvailablePositive3172288 - 317350247621.9
duf3575 domain-containing proteinIB64_RS13430Not AvailablePositive3174127 - 317469320937.5
duf3868 domain-containing proteinIB64_RS13435Not AvailablePositive3174708 - 317582042658.2
clostripain-related cysteine peptidaseIB64_RS13440Not AvailablePositive3175825 - 317696142239.3
duf5029 domain-containing proteinIB64_RS13445Not AvailablePositive3177199 - 317884559207.3
fimb/mfa2 family fimbrial subunitIB64_RS13450Not AvailablePositive3178940 - 317986334631.3
fimbrial proteinIB64_RS13455Not AvailablePositive3179890 - 318146156816.0
hypothetical proteinIB64_RS13460Not AvailablePositive3181480 - 318259240675.6

Displaying genes 2651 – 2660 of 4592 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total