Bacteroides fragilis strain DCMOUH0085B

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain DCMOUH0085B is a Gram-negative, mesophilic anaerobic bacterium characterized by its rod shape and the presence of flagella. It is classified as a chemoorganotroph, utilizing organic compounds as its energy source. This strain typically lives in association with hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes, indicating a versatile ecological niche. The bacterium is known to exist as singles, rather than in clusters, and has a single replicon and a double membrane structure. Its optimal growth temperature is 37°C, aligning with the typical human body temperature, which may facilitate its pathogenic interactions. Bacteroides fragilis is associated with a range of health implications, particularly in humans, where it can lead to serious conditions such as bacteremia, abscesses, and various gastrointestinal diseases, including diarrhea, colitis, and colorectal cancer. Its pathogenicity is underscored by its capacity to cause anaerobic bacteremia and intraabdominal abscesses, contributing to local tissue infections and septicemia. The ecological role of Bacteroides fragilis strain DCMOUH0085B highlights its dual nature as a free-living organism that can thrive in the human microbiome, while also posing significant health risks. This duality illustrates the complex interactions between host-associated microbes and their potential to influence both health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain DCMOUH0085B

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain DCMOUH0085B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain DCMOUH0085B chromosome, complete

Gene Summary

Adenine Count

1549643 bp

Thymine Count

1554580 bp

Guanine Count

1194780 bp

Cytosine Count

1205073 bp

Genome Length

5504076 bp

Protein-coding Genes

4471 genes

Non-Coding Genes

121 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-gluNot AvailableNot AvailablePositive1173856 - 1173930Not Available
dna repair protein recoIB64_RS04915Not AvailablePositive1174229 - 117495728217.4
gatb/yqey domain-containing proteinIB64_RS04920Not AvailableNegative1175122 - 117557116109.7
cell division protein ftszIB64_RS04925Not AvailableNegative1175655 - 117696547840.2
cell division protein ftsaIB64_RS04930Not AvailableNegative1176992 - 117842253109.9
cell division protein ftsq/divibIB64_RS04935Not AvailableNegative1178499 - 117923928028.9
udp-n-acetylmuramate--l-alanine ligaseIB64_RS04940Not AvailableNegative1179271 - 118066551812.9
undecaprenyldiphospho-muramoylpentapeptide beta-n-acetylglucosaminyltransferaseIB64_RS04945Not AvailableNegative1180662 - 118180441198.5
ftsw/roda/spove family cell cycle proteinIB64_RS04950Not AvailableNegative1181806 - 118310147177.9
udp-n-acetylmuramoyl-l-alanine--d-glutamate ligaseIB64_RS04955Not AvailableNegative1183160 - 118449449498.1

Displaying genes 1001 – 1010 of 4592 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total