Bacteroides fragilis strain DCMOUH0042B

Bacteroides fragilis strain DCMOUH0042B is a Gram-negative, rod-shaped anaerobe classified as a chemoorganotroph, utilizing organic compounds for energy. This organism is notable for its habitat association with various hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes. The strain typically exists as single cells and does not exhibit mobility, though it possesses flagella. This bacterium thrives optimally at a temperature of 37°C, which aligns with its mesophilic classification. It features two replicons and possesses a double-membrane structure, characteristic of its Gram-negative nature. Bacteroides fragilis strain DCMOUH0042B has been implicated in several health issues, demonstrating pathogenicity in humans. It is associated with conditions such as bacteremia, abscesses, Alzheimer’s disease pathologies, diarrhea, colitis, septicemia, colorectal cancer (CRC), and various local tissue infections. The strain's ability to cause anaerobic bacteremia and soft-tissue infections highlights its clinical significance, particularly in immunocompromised individuals. The biological insights regarding Bacteroides fragilis strain DCMOUH0042B underscore its role in both health and disease. As a free-living organism associated with multiple hosts, it contributes to the complex microbiota of the gastrointestinal tract, influencing human health and disease states. Understanding its pathogenic potential and ecological roles can inform treatment strategies and microbial management in clinical settings.