Bacteroides fragilis strain DCMOUH0018B

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain DCMOUH0018B is a Gram-negative, anaerobic, rod-shaped bacterium that primarily exists in association with hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes. This organism is a chemoorganotroph, utilizing organic compounds as its energy source. Its optimal growth temperature is 37°C, and it thrives within a mesophilic temperature range. The strain is characterized by its cell arrangement as singles and possesses flagella, although it exhibits no mobility. Bacteroides fragilis strain DCMOUH0018B has a complex genomic structure, consisting of four replicons and two membranes. In terms of its ecological role, it is classified as free-living, contributing to the microbiome of its hosts. However, this bacterium is also associated with various health effects, particularly in humans. It has been linked to serious medical conditions including bacteremia, abscesses, Alzheimer’s Disease pathologies, diarrhea, colitis, septicemia, colorectal cancer, and local tissue infections. The pathogenic potential of Bacteroides fragilis underscores its significance in both health and disease contexts. Understanding the dual roles of Bacteroides fragilis strain DCMOUH0018B as both a commensal organism within the microbiome and a potential pathogen highlights the complexity of host-microbe interactions. This strain exemplifies how microbial communities can influence health outcomes, particularly in the context of anaerobic infections and inflammatory diseases.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain DCMOUH0018B

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain DCMOUH0018B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain DCMOUH0018B chromosome, complete

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
metal abc transporter atp-binding proteinEE52_RS04345Q9Z810Negative991758 - 99257029932.0
metal abc transporter solute-binding protein, zn/mn familyEE52_RS04350Not AvailableNegative992718 - 99365334765.4
trna (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase mnmdEE52_RS04355A0KJJ9Negative993744 - 99449928178.6
yqaa family proteinEE52_RS04360Not AvailableNegative994511 - 99498717445.1
hypothetical proteinEE52_RS04365Not AvailableNegative994972 - 99596437634.9
phosphoribosylamine--glycine ligaseEE52_RS04370P57829Negative995964 - 99723845892.5
s9 family peptidaseEE52_RS04375Q7MUW6Negative997261 - 99940580652.1
class i sam-dependent rna methyltransferaseEE52_RS04380Q55156Negative999568 - 100090851261.9
serine o-acetyltransferaseEE52_RS04385Q59967Negative1000985 - 100188432548.1
histidine kinaseEE52_RS04390P94513Positive1002011 - 100404178518.3

Displaying genes 881 – 890 of 4134 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total