Bacteroides fragilis strain DCMOUH0018B

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain DCMOUH0018B is a Gram-negative, anaerobic, rod-shaped bacterium that primarily exists in association with hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes. This organism is a chemoorganotroph, utilizing organic compounds as its energy source. Its optimal growth temperature is 37°C, and it thrives within a mesophilic temperature range. The strain is characterized by its cell arrangement as singles and possesses flagella, although it exhibits no mobility. Bacteroides fragilis strain DCMOUH0018B has a complex genomic structure, consisting of four replicons and two membranes. In terms of its ecological role, it is classified as free-living, contributing to the microbiome of its hosts. However, this bacterium is also associated with various health effects, particularly in humans. It has been linked to serious medical conditions including bacteremia, abscesses, Alzheimer’s Disease pathologies, diarrhea, colitis, septicemia, colorectal cancer, and local tissue infections. The pathogenic potential of Bacteroides fragilis underscores its significance in both health and disease contexts. Understanding the dual roles of Bacteroides fragilis strain DCMOUH0018B as both a commensal organism within the microbiome and a potential pathogen highlights the complexity of host-microbe interactions. This strain exemplifies how microbial communities can influence health outcomes, particularly in the context of anaerobic infections and inflammatory diseases.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain DCMOUH0018B

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain DCMOUH0018B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain DCMOUH0018B chromosome, complete

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nudix domain-containing proteinEE52_RS00380Q8Y9Z9Positive74731 - 7526119666.0
glutathione peroxidaseEE52_RS00385Q9Z9N7Negative75381 - 7592320399.6
gh92 family glycosyl hydrolaseEE52_RS00390Not AvailableNegative75986 - 7832887941.0
cusa/czca family heavy metal efflux rnd transporterEE52_RS00395Not AvailablePositive78507 - 82826160249.0
efflux rnd transporter periplasmic adaptor subunitEE52_RS00400Not AvailablePositive82847 - 8373432166.9
sensor histidine kinaseEE52_RS00405P0AD15Positive83763 - 8482441125.2
lyttr family dna-binding domain-containing proteinEE52_RS00410Not AvailablePositive84821 - 8560029670.1
monomericEE52_RS00415Not AvailablePositive85689 - 8715854544.9
[fefe] hydrogenase h-cluster radical sam maturase hydeEE52_RS00420Q9X0Z6Positive87139 - 8817639634.6
[fefe] hydrogenase h-cluster radical sam maturase hydgEE52_RS00425Not AvailablePositive88189 - 8960753698.2

Displaying genes 111 – 120 of 4134 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total