Bacteroides fragilis strain DCMOUH0018B

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain DCMOUH0018B is a Gram-negative, anaerobic, rod-shaped bacterium that primarily exists in association with hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes. This organism is a chemoorganotroph, utilizing organic compounds as its energy source. Its optimal growth temperature is 37°C, and it thrives within a mesophilic temperature range. The strain is characterized by its cell arrangement as singles and possesses flagella, although it exhibits no mobility. Bacteroides fragilis strain DCMOUH0018B has a complex genomic structure, consisting of four replicons and two membranes. In terms of its ecological role, it is classified as free-living, contributing to the microbiome of its hosts. However, this bacterium is also associated with various health effects, particularly in humans. It has been linked to serious medical conditions including bacteremia, abscesses, Alzheimer’s Disease pathologies, diarrhea, colitis, septicemia, colorectal cancer, and local tissue infections. The pathogenic potential of Bacteroides fragilis underscores its significance in both health and disease contexts. Understanding the dual roles of Bacteroides fragilis strain DCMOUH0018B as both a commensal organism within the microbiome and a potential pathogen highlights the complexity of host-microbe interactions. This strain exemplifies how microbial communities can influence health outcomes, particularly in the context of anaerobic infections and inflammatory diseases.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain DCMOUH0018B

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain DCMOUH0018B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain DCMOUH0018B chromosome, complete

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
head gin domain-containing proteinEE52_RS04905Not AvailableNegative1119978 - 112071225889.5
sprt family zinc-dependent metalloproteaseEE52_RS04910Not AvailablePositive1120833 - 112153127189.4
hypothetical proteinEE52_RS04915Not AvailableNegative1121727 - 112212514952.2
gntr family transcriptional regulatorEE52_RS04920Not AvailablePositive1122354 - 112331636848.5
l-fucose isomeraseEE52_RS04925Q64ZS4Positive1123389 - 112516165414.9
lactaldehyde reductaseEE52_RS04930P0A9S2Positive1125180 - 112633440836.7
class ii aldolase/adducin family proteinEE52_RS04935Q57199Positive1126331 - 112696923576.2
rhamnulokinase family proteinEE52_RS04940Q8A1A3Positive1126989 - 112840152281.6
l-fucose:h+ symporter permeaseEE52_RS04945P44776Positive1128413 - 112974449263.0
hypothetical proteinEE52_RS04950Not AvailablePositive1129746 - 113086143602.5

Displaying genes 991 – 1000 of 4134 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total