Akkermansia muciniphila strain 139

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain 139 is a Gram-negative, anaerobic cocci bacterium that is associated with host organisms, particularly in Homo sapiens and Metazoa. This strain typically exists in pairs or singles and exhibits a mesophilic temperature range, with an optimal growth temperature of 37°C. Notably, it possesses two membranes and a single replicon, which are characteristic features of its cellular structure. A. muciniphila strain 139 is non-motile and does not produce flagella, indicating that it does not move independently but may rely on its environment for distribution. This strain is free-living, suggesting it can thrive in the intestinal environment where it plays a role in the microbiome. The bacterium has been associated with specific health effects, including food allergies and the thinning of the jejunum mucus layer. These observations highlight its potential impact on gut health and illustrate the delicate balance of microbiota in relation to host well-being. The ecological insight provided by A. muciniphila strain 139 emphasizes the importance of this bacterium in maintaining gut integrity and the potential consequences of its dysregulation. Understanding its role within the human microbiome can contribute to future research on gut health, immune responses, and the development of therapeutic strategies for food-related health issues. The accession number for this strain is NZ_CP036293.1, which can be referenced for further genomic analysis and studies.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain 139

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain 139
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain 139 chromosome, complete genome.

Gene Summary

Adenine Count

622875 bp

Thymine Count

617287 bp

Guanine Count

780467 bp

Cytosine Count

781288 bp

Genome Length

2801917 bp

Protein-coding Genes

2319 genes

Non-Coding Genes

66 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
deoxycytidylate deaminaseEYB66_RS00805Not AvailablePositive170063 - 17053017234.6
hypothetical proteinEYB66_RS00810Not AvailableNegative170542 - 17100315868.8
osmc family proteinEYB66_RS00815Not AvailableNegative171135 - 17154214478.6
protein-disulfide reductase dsbd family proteinEYB66_RS00820Not AvailablePositive171624 - 17393983704.5
gdsl-type esterase/lipase family proteinEYB66_RS00825Not AvailableNegative174015 - 17474627233.0
3'-5' exonucleaseEYB66_RS00830Not AvailableNegative174798 - 17539121276.7
dna mismatch repair protein mutsEYB66_RS00835Not AvailableNegative175393 - 17789493259.2
ribosome silencing factorEYB66_RS00840Not AvailableNegative178210 - 17856013003.7
atp-dependent zinc metalloprotease ftshEYB66_RS00845Not AvailableNegative178582 - 18103289970.7
hypothetical proteinEYB66_RS00850Not AvailableNegative181197 - 18199430637.7

Displaying genes 161 – 170 of 2385 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total