Campylobacter coli strain RM2228

Gram-negativeMicroaerophile

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter coli strain RM2228 is a Gram-negative bacterium classified as a microaerophile, indicating that it requires reduced levels of oxygen for optimal growth. This strain possesses a single replicon, suggesting a streamlined genomic structure typical of many bacteria in the Campylobacter genus. C. coli is known to infect various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and Bos (cattle). This broad host range is significant as it highlights the potential for zoonotic transmission, where infections can be passed from animals to humans. The health impacts associated with this strain are notable, as it can lead to a variety of serious health issues. These include bloodstream infections, urinary tract infections, and gastrointestinal diseases such as intestinal campylobacteriosis, enteritis, and acute bacterial enteritis, further classified under diarrheal diseases and enteric diseases. The genome of Campylobacter coli strain RM2228 can be accessed through the accession number NZ_CP035927.1. Understanding the biology and ecology of C. coli is crucial, especially regarding its role in foodborne illnesses. Given its prevalence in poultry and cattle, this strain poses a significant risk for human infections, particularly through the consumption of contaminated food or water. Efforts to monitor and control this pathogen in agricultural settings may help mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter coli
Strainstrain RM2228

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Campylobacter coli strain RM2228
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Campylobacter coli strain RM2228 chromosome, complete genome.

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1694 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
metal abc transporter solute-binding protein, zn/mn familyCCO2228_RS08110Not AvailablePositive1592468 - 159332233149.5
metal abc transporter atp-binding proteinCCO2228_RS08115Not AvailablePositive1593335 - 159418932546.6
metal abc transporter permeaseCCO2228_RS08120Not AvailablePositive1594182 - 159498829464.7
duf262 domain-containing proteinCCO2228_RS08125Not AvailableNegative1595231 - 159692867141.7
hypothetical proteinCCO2228_RS08130Not AvailableNegative1596985 - 159736515108.0
hypothetical proteinCCO2228_RS08135Not AvailableNegative1597437 - 159772411553.6
ribosome maturation factor rimpCCO2228_RS08140Not AvailableNegative1597797 - 159824016886.2
30s ribosome-binding factor rbfaCCO2228_RS08145Not AvailableNegative1598230 - 159859214303.1
translation initiation factor if-2CCO2228_RS08150Not AvailableNegative1598589 - 160115993862.0
duf448 domain-containing proteinCCO2228_RS08155Not AvailableNegative1601146 - 16013799082.24

Displaying genes 1631 – 1640 of 1752 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Intestinal campylobacteriosisCausesPMC10942002
CampylobacteriosisCausesPMC11434686
Diarrheal diseasesCausesPMC11434686
EnteritisCausesPMC13255289
Bloodstream infectionsCausesPMC13255289
Urinary tract infectionsCausesPMC13255289
Bacterial enteritisCausesPMC4108124
Acute bacterial enteritisCausesPMC4108124
Enteric diseaseCausesPMC9565744
CampylobacteriosisCausesPMC9565744

Displaying health effects 1 – 10 of 12 in total