Campylobacter coli strain RM2228

Gram-negativeMicroaerophile

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter coli strain RM2228 is a Gram-negative bacterium classified as a microaerophile, indicating that it requires reduced levels of oxygen for optimal growth. This strain possesses a single replicon, suggesting a streamlined genomic structure typical of many bacteria in the Campylobacter genus. C. coli is known to infect various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and Bos (cattle). This broad host range is significant as it highlights the potential for zoonotic transmission, where infections can be passed from animals to humans. The health impacts associated with this strain are notable, as it can lead to a variety of serious health issues. These include bloodstream infections, urinary tract infections, and gastrointestinal diseases such as intestinal campylobacteriosis, enteritis, and acute bacterial enteritis, further classified under diarrheal diseases and enteric diseases. The genome of Campylobacter coli strain RM2228 can be accessed through the accession number NZ_CP035927.1. Understanding the biology and ecology of C. coli is crucial, especially regarding its role in foodborne illnesses. Given its prevalence in poultry and cattle, this strain poses a significant risk for human infections, particularly through the consumption of contaminated food or water. Efforts to monitor and control this pathogen in agricultural settings may help mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter coli
Strainstrain RM2228

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Campylobacter coli strain RM2228
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Campylobacter coli strain RM2228 chromosome, complete genome.

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1694 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
arss family sensor histidine kinaseCCO2228_RS06120Not AvailableNegative1196912 - 119816248707.1
response regulator transcription factorCCO2228_RS06125Not AvailableNegative1198159 - 119883325492.8
degq family serine endoproteaseCCO2228_RS06130Not AvailableNegative1198916 - 120033451467.3
dnaj family proteinCCO2228_RS06135Not AvailablePositive1200540 - 120143933294.4
heat shock transcriptional regulator hsprCCO2228_RS06140Not AvailablePositive1201456 - 120183014552.7
cation:proton antiporterCCO2228_RS06145Not AvailablePositive1201831 - 120345359759.9
hypothetical proteinCCO2228_RS06150Not AvailablePositive1203463 - 120379513010.7
had family hydrolaseCCO2228_RS06155Not AvailablePositive1203788 - 120440823769.4
glycine--trna ligase subunit betaCCO2228_RS06160Not AvailablePositive1204461 - 120645576379.0
m23 family metallopeptidaseCCO2228_RS06165Not AvailablePositive1206452 - 120727330588.9

Displaying genes 1231 – 1240 of 1752 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Intestinal campylobacteriosisCausesPMC10942002
CampylobacteriosisCausesPMC11434686
Diarrheal diseasesCausesPMC11434686
EnteritisCausesPMC13255289
Bloodstream infectionsCausesPMC13255289
Urinary tract infectionsCausesPMC13255289
Bacterial enteritisCausesPMC4108124
Acute bacterial enteritisCausesPMC4108124
Enteric diseaseCausesPMC9565744
CampylobacteriosisCausesPMC9565744

Displaying health effects 1 – 10 of 12 in total