Enterobacter cloacae strain CZ-1

Enterobacter cloacae strain CZ-1 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism, allowing it to thrive in various oxygen conditions. This strain is mesophilic, indicating it grows optimally at moderate temperatures. Importantly, it possesses flagella, but it is non-motile, suggesting that while it may have the potential for movement, it does not utilize this capability in its ecological interactions. As a free-living organism, Enterobacter cloacae strain CZ-1 can inhabit multiple environments and has notable biotic relationships with various hosts, including Homo sapiens, Bos (cattle), and Okapia johnstoni (okapi). Its pathogenicity is significant in humans, where it is associated with serious health conditions such as vertebral osteomyelitis, bacteremia, spondylodiscitis, and various bloodstream infections. This indicates its potential as an opportunistic pathogen, particularly in immunocompromised individuals. The strain has a single replicon and features a double-membrane structure, typical of Gram-negative bacteria, which contributes to its resilience and adaptability in diverse habitats. Overall, Enterobacter cloacae strain CZ-1 exemplifies the complex interplay between environmental adaptability and pathogenic potential, highlighting the need for careful monitoring in clinical and ecological contexts, especially given its association with multiple serious infections in humans.