Enterobacter cloacae strain EN3600

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Enterobacter

Description

Enterobacter cloacae strain EN3600 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It possesses flagella, which indicates its potential for motility despite being noted as non-mobile. The strain thrives in mesophilic temperature ranges and exhibits a complex genetic structure with three replicons. This strain is known to inhabit multiple environments and maintains a free-living biotic relationship. It has been associated with various hosts, including Homo sapiens, Bos, and Okapia johnstoni. Enterobacter cloacae strain EN3600 is of particular clinical significance due to its pathogenicity in humans, where it has been linked to several serious health effects, including vertebral osteomyelitis, bacteremia, spondylodiscitis, and both urinary and respiratory tract infections. The presence of this strain in human infections highlights its role as an opportunistic pathogen, particularly in individuals with compromised health. Given its diverse habitat and ability to infect multiple hosts, Enterobacter cloacae strain EN3600 serves as an important example of how environmental factors can influence microbial pathogenicity and health outcomes. Understanding its ecological interactions and pathogenic potential can inform strategies for managing infections and developing treatments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEnterobacter
SpeciesEnterobacter cloacae
Strainstrain EN3600

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Enterobacter cloacae strain EN3600
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Okapia johnstoni
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterobacter cloacae strain EN3600 plasmid unnamed4, complete

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

110 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
oxacillin-hydrolyzing class d beta-lactamase oxa-1EVV94_RS25920Not AvailablePositive12323 - 1315330881.8
AcetyltransferaseEVV94_RS25925Not AvailablePositive13291 - 1392323618.2
nad(+)--rifampin adp-ribosyltransferase arr-3EVV94_RS25930Not AvailablePositive14008 - 1446016969.3
Putative quaternary ammonium compound-resistance protein qaceEVV94_RS25935Not AvailablePositive14683 - 1503012332.6
sulfonamide-resistant dihydropteroate synthase sul1EVV94_RS25940Not AvailablePositive15024 - 1586330128.0
hypothetical proteinEVV94_RS25950Not AvailablePositive15991 - 162639877.58
Is110 family transposaseEVV94_RS25955Not AvailableNegative16445 - 1744937469.7
chromate efflux transporterEVV94_RS25960Not AvailablePositive17677 - 1888242278.4
padr family transcriptional regulatorEVV94_RS25965Not AvailablePositive18893 - 1919811477.8
eal domain-containing proteinEVV94_RS28220Not AvailablePositive19242 - 193072357.93

Displaying genes 221 – 230 of 335 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Vertebral osteomyelitisCausesPMC1004780
BacteremiaCausesPMC1004780
SpondylodiscitisCausesPMC1004780
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
BsiCausesPMC10545569
Urinary and respiratory tract infectionsCausesPMC8956555

Displaying health effects 1 – 7 of 7 in total