Enterobacter cloacae strain EN3600

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Enterobacter

Description

Enterobacter cloacae strain EN3600 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It possesses flagella, which indicates its potential for motility despite being noted as non-mobile. The strain thrives in mesophilic temperature ranges and exhibits a complex genetic structure with three replicons. This strain is known to inhabit multiple environments and maintains a free-living biotic relationship. It has been associated with various hosts, including Homo sapiens, Bos, and Okapia johnstoni. Enterobacter cloacae strain EN3600 is of particular clinical significance due to its pathogenicity in humans, where it has been linked to several serious health effects, including vertebral osteomyelitis, bacteremia, spondylodiscitis, and both urinary and respiratory tract infections. The presence of this strain in human infections highlights its role as an opportunistic pathogen, particularly in individuals with compromised health. Given its diverse habitat and ability to infect multiple hosts, Enterobacter cloacae strain EN3600 serves as an important example of how environmental factors can influence microbial pathogenicity and health outcomes. Understanding its ecological interactions and pathogenic potential can inform strategies for managing infections and developing treatments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEnterobacter
SpeciesEnterobacter cloacae
Strainstrain EN3600

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Enterobacter cloacae strain EN3600
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Okapia johnstoni
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterobacter cloacae strain EN3600


Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

110 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
copper/silver response regulator transcription factor silrEVV94_RS26560Not AvailableNegative9516 - 1019625178.8
cu(+)/ag(+) efflux rnd transporter outer membrane channel silcEVV94_RS26565Not AvailablePositive10386 - 1177151231.6
cation efflux system protein cusfEVV94_RS26570Not AvailablePositive11800 - 1215312592.1
cu(+)/ag(+) efflux rnd transporter periplasmic adaptor subunit silbEVV94_RS26575Not AvailablePositive12267 - 1355947773.4
cu(+)/ag(+) efflux rnd transporter permease subunit silaEVV94_RS26580Not AvailablePositive13570 - 16716114580.0
duf411 domain-containing proteinEVV94_RS26585Not AvailablePositive16803 - 1724315506.1
sdr family nad(p)-dependent oxidoreductaseEVV94_RS28665Not AvailablePositive17370 - 1854843397.7
sdr family nad(p)-dependent oxidoreductaseEVV94_RS28670Not AvailablePositive18661 - 1994744301.7
duf2933 domain-containing proteinEVV94_RS26600Not AvailablePositive19988 - 201857284.78
peptidoglycan dd-metalloendopeptidase family proteinEVV94_RS26605Not AvailableNegative20219 - 2095627203.3

Displaying genes 11 – 20 of 335 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Vertebral osteomyelitisCausesPMC1004780
BacteremiaCausesPMC1004780
SpondylodiscitisCausesPMC1004780
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
BsiCausesPMC10545569
Urinary and respiratory tract infectionsCausesPMC8956555

Displaying health effects 1 – 7 of 7 in total