Enterobacter cloacae strain EN3600

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Enterobacter

Description

Enterobacter cloacae strain EN3600 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It possesses flagella, which indicates its potential for motility despite being noted as non-mobile. The strain thrives in mesophilic temperature ranges and exhibits a complex genetic structure with three replicons. This strain is known to inhabit multiple environments and maintains a free-living biotic relationship. It has been associated with various hosts, including Homo sapiens, Bos, and Okapia johnstoni. Enterobacter cloacae strain EN3600 is of particular clinical significance due to its pathogenicity in humans, where it has been linked to several serious health effects, including vertebral osteomyelitis, bacteremia, spondylodiscitis, and both urinary and respiratory tract infections. The presence of this strain in human infections highlights its role as an opportunistic pathogen, particularly in individuals with compromised health. Given its diverse habitat and ability to infect multiple hosts, Enterobacter cloacae strain EN3600 serves as an important example of how environmental factors can influence microbial pathogenicity and health outcomes. Understanding its ecological interactions and pathogenic potential can inform strategies for managing infections and developing treatments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEnterobacter
SpeciesEnterobacter cloacae
Strainstrain EN3600

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Enterobacter cloacae strain EN3600
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Okapia johnstoni
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterobacter cloacae strain EN3600 plasmid unnamed4, complete

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

110 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lysr family transcriptional regulatorEVV94_RS26985Not AvailableNegative85351 - 8625033507.5
cyclophilin-like fold proteinEVV94_RS26990Not AvailablePositive86367 - 8682816662.0
mfs transporterEVV94_RS26995Not AvailablePositive86956 - 8817342756.6
nad(p)-dependent alcohol dehydrogenaseEVV94_RS27000Not AvailablePositive88190 - 8923637190.6
alpha/beta hydrolaseEVV94_RS27005Not AvailablePositive89253 - 9028137992.1
aldo/keto reductaseEVV94_RS27010Not AvailablePositive90307 - 9129336418.4
sdr family nad(p)-dependent oxidoreductaseEVV94_RS27015Not AvailablePositive91657 - 9247228677.5
sdr family nad(p)-dependent oxidoreductaseEVV94_RS27020Not AvailablePositive92502 - 9325727190.6
duf1380 domain-containing proteinEVV94_RS27025Not AvailableNegative93223 - 9355812723.3
hypothetical proteinEVV94_RS27030Not AvailableNegative93656 - 938778375.06

Displaying genes 91 – 100 of 335 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Vertebral osteomyelitisCausesPMC1004780
BacteremiaCausesPMC1004780
SpondylodiscitisCausesPMC1004780
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
BsiCausesPMC10545569
Urinary and respiratory tract infectionsCausesPMC8956555

Displaying health effects 1 – 7 of 7 in total