Staphylococcus haemolyticus strain PK-01

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus haemolyticus strain PK-01 is a Gram-positive, cocci-shaped bacterium classified as a chemoheterotroph and a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. This strain is nonmotile and lacks flagella, suggesting that it does not move independently. It has an optimal growth temperature of 37°C and falls within the mesophilic temperature range, which is conducive to growth in warm-blooded hosts. The strain has been identified in multiple habitats and is associated with various hosts, including Homo sapiens (humans), Bos taurus (cattle), Metazoa (multicellular animals), Canis lupus familiaris (domestic dogs), Felis catus (domestic cats), and Phocidae (seals). This broad host range highlights its ecological versatility and potential for zoonotic transmission. Clinically, S. haemolyticus strain PK-01 is known to cause a variety of health issues, including meningitis, skin and soft tissue infections, bloodstream infections, bovine mastitis, native valve endocarditis, prosthetic joint infections, catheter-related bloodstream infections, nosocomial meningitis, and gangrenous mastitis. These health effects underscore its significance as an opportunistic pathogen, particularly in hospital settings and among immunocompromised individuals. The strain's capacity to inhabit diverse environments and infect multiple host species suggests a complex ecological role, potentially contributing to the persistence of antibiotic-resistant strains in both human and veterinary medicine. This adaptability emphasizes the importance of continuous monitoring and research to understand its epidemiology and impact on public health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus haemolyticus
Strainstrain PK-01

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Staphylococcus haemolyticus strain PK-01
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens, Bos taurus, Metazoa
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Staphylococcus haemolyticus strain PK-01 chromosome, complete

Gene Summary

Adenine Count

883496 bp

Thymine Count

873714 bp

Guanine Count

433116 bp

Cytosine Count

425357 bp

Genome Length

2615683 bp

Protein-coding Genes

2564 genes

Non-Coding Genes

140 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glycoside hydrolase family 25 proteinEU512_RS12570Not AvailablePositive2496257 - 249706330302.6
hypothetical proteinEU512_RS12575Not AvailablePositive2497129 - 24973207366.77
redox-regulated atpase ychfEU512_RS12580Not AvailableNegative2497462 - 249855940714.3
duf951 domain-containing proteinEU512_RS12585Not AvailableNegative2498571 - 24987747759.6
mechanosensitive ion channel family proteinEU512_RS12590Not AvailableNegative2498796 - 249967732268.6
parb/repb/spo0j family partition proteinEU512_RS12595Not AvailableNegative2499858 - 250068831683.3
plp-dependent transferaseEU512_RS12600Not AvailablePositive2501498 - 250260140913.7
cystathionine beta-lyase metcEU512_RS12605Not AvailablePositive2502598 - 250377342669.7
bifunctional homocysteine s-methyltransferase/methylenetetrahydrofolate reductaseEU512_RS12610Not AvailablePositive2503727 - 250556568022.3
5-methyltetrahydropteroyltriglutamate-- homocysteine s-methyltransferaseEU512_RS12615Not AvailablePositive2505562 - 250781185454.0

Displaying genes 2531 – 2540 of 2704 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Bovine mastitisCausesPMC13280230
MastitisCausesPMC13280230
Native valve endocarditisCausesPMC4486112
Prosthetic join infectionsCausesPMC4486112
MeningitisCausesPMC4486112
Skin and soft tissue infectionsCausesPMC4486112
Catheter-related bloodstream infectionsCausesPMC4486112
Nosocomial meningitisCausesPMC9930307
MeningitisCausesPMC9930307
Bloodstream infectionsCausesPMC8471643

Displaying health effects 1 – 10 of 11 in total