Escherichia coli O157:H7 strain FWSEC0004

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli O157:H7 strain FWSEC0004 is a pathogenic bacterium primarily associated with various hosts, including Homo sapiens (humans), Bos taurus (cattle), Sus scrofa (pigs), and Oryctolagus cuniculus (rabbits). This strain is classified as a Gram-negative, rod-shaped organism that can exist in pairs or singles. It possesses flagella, which allows for mobility, and is a facultative anaerobe, enabling it to survive in both aerobic and anaerobic environments. The optimal temperature for growth of E. coli O157:H7 FWSEC0004 is 37°C, placing it within the mesophilic temperature range. The bacterium has two replicons and is characterized by a double membrane structure. In terms of its ecological role, it is classified as free-living, indicating its ability to survive independently in various environments. Health effects associated with E. coli O157:H7 FWSEC0004 include diarrhea, hemorrhagic diarrhea, renal failure, anemia, and hemolytic uremic syndrome (HUS), a severe condition that can arise from infection. Given its pathogenic potential and association with multiple hosts, E. coli O157:H7 FWSEC0004 underscores the importance of understanding host interactions and environmental factors that facilitate its transmission and virulence. This strain exemplifies the complex relationships between bacterial pathogens and their animal reservoirs, highlighting the need for continuous monitoring in both clinical and agricultural settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainO157:H7 strain FWSEC0004

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli O157:H7 strain FWSEC0004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Bos taurus, Bos
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Escherichia coli O157:H7 strain FWSEC0004 chromosome, complete

Gene Summary

Adenine Count

1336162 bp

Thymine Count

1340115 bp

Guanine Count

1365483 bp

Cytosine Count

1364490 bp

Genome Length

5406250 bp

Protein-coding Genes

4555 genes

Non-Coding Genes

860 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ammonia-forming nitrite reductase cytochrome c552 subunitCAM50_RS25365Not AvailableNegative4974145 - 497558153705.7
acetate--coa ligaseCAM50_RS25370Not AvailablePositive4975974 - 497793272113.4
duf485 domain-containing proteinCAM50_RS25375Not AvailablePositive4978133 - 497844711658.3
cation/acetate symporter actpCAM50_RS25380Not AvailablePositive4978444 - 498009359227.8
t3ss effector pentapeptide repeat protein espx5CAM50_RS25385Not AvailablePositive4980274 - 498156649623.3
na+/h+ antiporterCAM50_RS25390Not AvailableNegative4981720 - 498336960527.5
guanine/hypoxanthine transporter ghxpCAM50_RS25395Not AvailableNegative4983520 - 498486945714.4
redox-sensitive transcriptional activator soxrCAM50_RS25400Not AvailableNegative4985415 - 498587917150.7
superoxide response transcriptional regulator soxsCAM50_RS25405Not AvailablePositive4985965 - 498628812911.6
c-di-gmp phosphodiesterase pdecCAM50_RS25410Not AvailableNegative4986291 - 498787760744.7

Displaying genes 5021 – 5030 of 5425 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
DiarrheaCausesPMC3035056
Hemorrhagic diarrheaCausesPMC4726323
Renal failureCausesPMC4726323
AnemiaCausesPMC4726323
HusCausesPMC7320338
Hemolytic uremic syndromeCausesPMC7320338
Hemorrhagic colitisCausesPMC13022023
HusCausesPMC13022023
Hemolytic uremic syndromeCausesPMC3338595
Hemorrhagic colitisCausesPMC3667801

Displaying health effects 1 – 10 of 12 in total