Escherichia coli strain CFSAN064035

Escherichia coli strain CFSAN064035 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. This strain is characterized by its ability to exist in pairs or as singles and possesses two replicons and two membranes. CFSAN064035 is host-associated and is known to inhabit a diverse range of hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), Bos taurus (cattle), and various other mammals, birds, and even some plants like Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). The biotic relationship of this strain is categorized as free-living, indicating its adaptability to various environments. This strain is notably pathogenic to humans, associated with a wide array of health effects. These include urinary tract infections (UTIs), gastrointestinal infections, septicemia, and complications such as hemolytic uremic syndrome (HUS) and neonatal meningitis. The extensive list of potential health impacts underscores its significance in clinical microbiology, particularly concerning foodborne infections and enteric diseases. The ecological insight from the diverse host range of CFSAN064035 suggests its role as a significant pathogen in both human health and animal agriculture. The strain's adaptability to various hosts and environments highlights the importance of surveillance and control measures in mitigating its impact on public health and veterinary medicine.