Corynebacterium diphtheriae strain BQ11

Gram-positiveRodNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Corynebacterium diphtheriae strain BQ11 is a Gram-positive, non-motile rod-shaped bacterium that is classified as an aerobe. It is mesophilic, with an optimal growth temperature of 37°C, making it well-suited to thrive within the human body, specifically as a pathogen in Homo sapiens. This strain has been linked to significant health effects, including endocarditis, diphtheria, and systemic disease. Corynebacterium diphtheriae is notable for its single replicon and one membrane structure, indicating a streamlined genomic organization that is typical of many pathogenic bacteria. The presence of flagella is documented, which is somewhat atypical for non-motile strains, suggesting potential complexities in its motility or interaction with host tissues. The ability of C. diphtheriae to inhabit multiple environments highlights its adaptability, although the primary ecological niche appears to be within human hosts where it can cause serious infections. Understanding the specific habitats and growth conditions of C. diphtheriae may provide insights into its pathogenic mechanisms and potential strategies for controlling infections. In summary, Corynebacterium diphtheriae strain BQ11 is an important pathogen with specific traits that facilitate its survival and virulence within human hosts, underscoring the importance of monitoring and studying this bacterium in clinical microbiology. The accession number for this strain is NZ_CP029644.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium diphtheriae
Strainstrain BQ11

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Corynebacterium diphtheriae strain BQ11
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Corynebacterium diphtheriae strain BQ11 chromosome, complete

Gene Summary

Adenine Count

591798 bp

Thymine Count

594467 bp

Guanine Count

687989 bp

Cytosine Count

683127 bp

Genome Length

2557381 bp

Protein-coding Genes

2295 genes

Non-Coding Genes

141 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glyceraldehyde-3-phosphate dehydrogenaseB11Q_RS04845Not AvailableNegative930681 - 93211152050.0
hypothetical proteinB11Q_RS04850Not AvailablePositive932376 - 93302922815.9
hypothetical proteinB11Q_RS04855Not AvailablePositive933057 - 9332607684.5
peptide chain release factor 3B11Q_RS04860Not AvailableNegative933274 - 93490859711.7
sdr family nad(p)-dependent oxidoreductaseB11Q_RS04865Not AvailableNegative934920 - 93572929200.8
aminoacyl-trna hydrolaseB11Q_RS04870Not AvailableNegative935761 - 93639022357.9
hnh endonuclease signature motif containing proteinB11Q_RS04875Not AvailablePositive936582 - 93774543056.1
hypothetical proteinB11Q_RS12775Not AvailablePositive937759 - 9379386629.47
aminoacyl-trna hydrolaseB11Q_RS04885Not AvailableNegative937919 - 93847320200.6
50s ribosomal protein l25/general stress protein ctcB11Q_RS04890Not AvailableNegative938531 - 93914821934.8

Displaying genes 941 – 950 of 2436 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
DiphtheriaCausesPMC4152248
EndocarditisCausesPMC4152248
Systemic diseaseCausesPMC4152248
DiphtheriaCausesPMC8325488
DiphtheriaCausesPMC5944148

Displaying health effects 1 – 5 of 5 in total