Corynebacterium diphtheriae strain BQ11

Gram-positiveRodNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Corynebacterium diphtheriae strain BQ11 is a Gram-positive, non-motile rod-shaped bacterium that is classified as an aerobe. It is mesophilic, with an optimal growth temperature of 37°C, making it well-suited to thrive within the human body, specifically as a pathogen in Homo sapiens. This strain has been linked to significant health effects, including endocarditis, diphtheria, and systemic disease. Corynebacterium diphtheriae is notable for its single replicon and one membrane structure, indicating a streamlined genomic organization that is typical of many pathogenic bacteria. The presence of flagella is documented, which is somewhat atypical for non-motile strains, suggesting potential complexities in its motility or interaction with host tissues. The ability of C. diphtheriae to inhabit multiple environments highlights its adaptability, although the primary ecological niche appears to be within human hosts where it can cause serious infections. Understanding the specific habitats and growth conditions of C. diphtheriae may provide insights into its pathogenic mechanisms and potential strategies for controlling infections. In summary, Corynebacterium diphtheriae strain BQ11 is an important pathogen with specific traits that facilitate its survival and virulence within human hosts, underscoring the importance of monitoring and studying this bacterium in clinical microbiology. The accession number for this strain is NZ_CP029644.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium diphtheriae
Strainstrain BQ11

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Corynebacterium diphtheriae strain BQ11
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Corynebacterium diphtheriae strain BQ11 chromosome, complete

Gene Summary

Adenine Count

591798 bp

Thymine Count

594467 bp

Guanine Count

687989 bp

Cytosine Count

683127 bp

Genome Length

2557381 bp

Protein-coding Genes

2295 genes

Non-Coding Genes

141 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dihydroxyacetone kinase subunit dhakB11Q_RS12125Not AvailablePositive2509892 - 251088734496.1
dihydroxyacetone kinase subunit dhalB11Q_RS12130Not AvailablePositive2510891 - 251153221451.0
dihydroxyacetone kinase phosphoryl donor subunit dhamB11Q_RS12135Not AvailablePositive2511529 - 251219722110.0
aaa family atpaseB11Q_RS12140Not AvailablePositive2512383 - 251370250141.4
alpha/beta hydrolaseB11Q_RS12150Not AvailableNegative2514236 - 251545644781.9
nucleoside hydrolaseB11Q_RS12155Not AvailablePositive2515493 - 251648836024.7
glycosyl transferase family 9B11Q_RS12160Not AvailablePositive2516584 - 251734226758.1
energy-coupling factor transporter transmembrane protein ecftB11Q_RS12165Not AvailablePositive2517474 - 251804020521.9
atp-binding cassette domain-containing proteinB11Q_RS12170Not AvailablePositive2518060 - 251922641011.8
aldose epimeraseB11Q_RS12175Not AvailableNegative2519237 - 251996226535.2

Displaying genes 2391 – 2400 of 2436 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
DiphtheriaCausesPMC4152248
EndocarditisCausesPMC4152248
Systemic diseaseCausesPMC4152248
DiphtheriaCausesPMC8325488
DiphtheriaCausesPMC5944148

Displaying health effects 1 – 5 of 5 in total