Corynebacterium diphtheriae strain BQ11

Gram-positiveRodNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Corynebacterium diphtheriae strain BQ11 is a Gram-positive, non-motile rod-shaped bacterium that is classified as an aerobe. It is mesophilic, with an optimal growth temperature of 37°C, making it well-suited to thrive within the human body, specifically as a pathogen in Homo sapiens. This strain has been linked to significant health effects, including endocarditis, diphtheria, and systemic disease. Corynebacterium diphtheriae is notable for its single replicon and one membrane structure, indicating a streamlined genomic organization that is typical of many pathogenic bacteria. The presence of flagella is documented, which is somewhat atypical for non-motile strains, suggesting potential complexities in its motility or interaction with host tissues. The ability of C. diphtheriae to inhabit multiple environments highlights its adaptability, although the primary ecological niche appears to be within human hosts where it can cause serious infections. Understanding the specific habitats and growth conditions of C. diphtheriae may provide insights into its pathogenic mechanisms and potential strategies for controlling infections. In summary, Corynebacterium diphtheriae strain BQ11 is an important pathogen with specific traits that facilitate its survival and virulence within human hosts, underscoring the importance of monitoring and studying this bacterium in clinical microbiology. The accession number for this strain is NZ_CP029644.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium diphtheriae
Strainstrain BQ11

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Corynebacterium diphtheriae strain BQ11
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Corynebacterium diphtheriae strain BQ11 chromosome, complete

Gene Summary

Adenine Count

591798 bp

Thymine Count

594467 bp

Guanine Count

687989 bp

Cytosine Count

683127 bp

Genome Length

2557381 bp

Protein-coding Genes

2295 genes

Non-Coding Genes

141 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
membrane protein insertase yidcB11Q_RS12850Not AvailableNegative1637291 - 163807428651.1
hypothetical proteinB11Q_RS08155Not AvailablePositive1638223 - 163953646327.8
50s ribosomal protein l5B11Q_RS08160Not AvailableNegative1639739 - 164029020992.3
50s ribosomal protein l24B11Q_RS08165Not AvailableNegative1640293 - 164060711273.7
50s ribosomal protein l14B11Q_RS08170Not AvailableNegative1640610 - 164097813360.4
membrane protein insertase yidcB11Q_RS08175Not AvailablePositive1641530 - 164273742360.9
hypothetical proteinB11Q_RS08180Not AvailablePositive1643198 - 164410031945.5
integrase core domain-containing proteinB11Q_RS08185Not AvailableNegative1644442 - 164593556031.4
nadp-specific glutamate dehydrogenaseB11Q_RS08190Not AvailableNegative1646095 - 164744149056.1
glycerate kinaseB11Q_RS08195Not AvailablePositive1647858 - 164902440092.3

Displaying genes 1601 – 1610 of 2436 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
DiphtheriaCausesPMC4152248
EndocarditisCausesPMC4152248
Systemic diseaseCausesPMC4152248
DiphtheriaCausesPMC8325488
DiphtheriaCausesPMC5944148

Displaying health effects 1 – 5 of 5 in total