Cronobacter sakazakii strain GZcsf-1

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Cronobacter

Description

Cronobacter sakazakii strain GZcsf-1 is a Gram-negative, non-motile rod-shaped bacterium that primarily inhabits host-associated environments. This strain has been identified in various hosts, including Homo sapiens, Viridiplantae, Amphibia, Gastrotheca, and Cucumis sativus. It is classified as an anaerobe, indicating that it thrives in environments devoid of oxygen, which may influence its ecological niches. The optimal growth temperature for C. sakazakii GZcsf-1 is 37°C, placing it within the mesophilic temperature range. This temperature preference aligns with the body temperature of humans, suggesting an adaptation for pathogenicity in human hosts. The strain is characterized by its arrangement in pairs or singles and contains a single replicon, which is a notable trait among bacteria. C. sakazakii is known for its pathogenic potential, particularly in humans, where it can cause severe health issues such as meningitis, sepsis, septicemia, bacteraemia, bacterial meningitis, and necrotizing enterocolitis (NEC). The strain's involvement in mild diseases and serious complications like brain abscesses and lesions highlights its clinical significance. The presence of flagella suggests a potential for mobility, although the strain itself is categorized as non-motile. Understanding the habitat and pathogenic traits of C. sakazakii strain GZcsf-1 is crucial for assessing its ecological role and potential health risks, particularly in immunocompromised populations. The ability to thrive in diverse environments emphasizes its adaptability and the importance of monitoring its presence in both clinical and environmental settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusCronobacter
SpeciesCronobacter sakazakii
Strainstrain GZcsf-1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cronobacter sakazakii strain GZcsf-1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Amphibia
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Cronobacter sakazakii strain GZcsf-1 plasmid pGW1, complete

Gene Summary

Adenine Count

87220 bp

Thymine Count

87979 bp

Guanine Count

82178 bp

Cytosine Count

83346 bp

Genome Length

340723 bp

Protein-coding Genes

349 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf4225 domain-containing proteinDC438_RS21490Not AvailableNegative33868 - 3467429563.0
replication initiation proteinDC438_RS21500Not AvailableNegative35554 - 356945442.47
Is110 family transposaseDC438_RS21505Not AvailableNegative35974 - 3697837469.7
chromate efflux transporterDC438_RS21510Not AvailablePositive37206 - 3841142278.4
padr family transcriptional regulatorDC438_RS21515Not AvailablePositive38422 - 3872711477.8
ntp-binding proteinDC438_RS24440Not AvailableNegative38753 - 388663876.5
Transposase is26DC438_RS21525Not AvailablePositive38954 - 3971829684.0
macrolide-binding transcriptional repressor mphr(a)DC438_RS21540Not AvailableNegative40211 - 4079521629.4
macrolide resistance mfs transporter mrx(a)DC438_RS21545Not AvailableNegative40795 - 4203340959.1
mph(a) family macrolide 2'-phosphotransferaseDC438_RS21550Not AvailableNegative42030 - 4293533229.7

Displaying genes 51 – 60 of 405 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Mild diseasesCausesPMC5615607
Bacterial meningitisCausesPMC10370310
SepsisCausesPMC10370310
Necrotizing enterocolitisCausesPMC11267904
NecCausesPMC11267904
SepsisCausesPMC11267904
MeningitisCausesPMC11267904
Necrotizing enterocolitisCausesPMC1868726
BacteraemiaCausesPMC1868726
MeningitisCausesPMC1868726

Displaying health effects 1 – 10 of 19 in total