Cronobacter sakazakii strain GZcsf-1

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Cronobacter

Description

Cronobacter sakazakii strain GZcsf-1 is a Gram-negative, non-motile rod-shaped bacterium that primarily inhabits host-associated environments. This strain has been identified in various hosts, including Homo sapiens, Viridiplantae, Amphibia, Gastrotheca, and Cucumis sativus. It is classified as an anaerobe, indicating that it thrives in environments devoid of oxygen, which may influence its ecological niches. The optimal growth temperature for C. sakazakii GZcsf-1 is 37°C, placing it within the mesophilic temperature range. This temperature preference aligns with the body temperature of humans, suggesting an adaptation for pathogenicity in human hosts. The strain is characterized by its arrangement in pairs or singles and contains a single replicon, which is a notable trait among bacteria. C. sakazakii is known for its pathogenic potential, particularly in humans, where it can cause severe health issues such as meningitis, sepsis, septicemia, bacteraemia, bacterial meningitis, and necrotizing enterocolitis (NEC). The strain's involvement in mild diseases and serious complications like brain abscesses and lesions highlights its clinical significance. The presence of flagella suggests a potential for mobility, although the strain itself is categorized as non-motile. Understanding the habitat and pathogenic traits of C. sakazakii strain GZcsf-1 is crucial for assessing its ecological role and potential health risks, particularly in immunocompromised populations. The ability to thrive in diverse environments emphasizes its adaptability and the importance of monitoring its presence in both clinical and environmental settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusCronobacter
SpeciesCronobacter sakazakii
Strainstrain GZcsf-1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cronobacter sakazakii strain GZcsf-1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Amphibia
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Cronobacter sakazakii strain GZcsf-1 plasmid pGW1, complete

Gene Summary

Adenine Count

87220 bp

Thymine Count

87979 bp

Guanine Count

82178 bp

Cytosine Count

83346 bp

Genome Length

340723 bp

Protein-coding Genes

349 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinDC438_RS21780Not AvailableNegative75086 - 7543012875.5
h-ns family nucleoid-associated regulatory proteinDC438_RS21785Not AvailableNegative75446 - 7575111545.9
lytic transglycosylase domain-containing proteinDC438_RS21790Not AvailablePositive75860 - 7659725942.6
transcriptional repressor koraDC438_RS21795Not AvailablePositive76606 - 7688710959.2
conjugal transfer protein tramDC438_RS21800Not AvailablePositive76897 - 771217869.93
Transposase is26DC438_RS21805Not AvailableNegative77155 - 7785927896.9
AttrNot AvailableNot AvailablePositive77933 - 77944Not Available
Transposase is26DC438_RS22350Not AvailablePositive171403 - 17210727896.9
alpha/beta hydrolase-fold proteinDC438_RS22360Not AvailableNegative172153 - 17257515801.6
Zinc-containing alcohol dehydrogenase superfamily proteinDC438_RS22365Not AvailableNegative172597 - 17370639085.9

Displaying genes 91 – 100 of 405 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Mild diseasesCausesPMC5615607
Bacterial meningitisCausesPMC10370310
SepsisCausesPMC10370310
Necrotizing enterocolitisCausesPMC11267904
NecCausesPMC11267904
SepsisCausesPMC11267904
MeningitisCausesPMC11267904
Necrotizing enterocolitisCausesPMC1868726
BacteraemiaCausesPMC1868726
MeningitisCausesPMC1868726

Displaying health effects 1 – 10 of 19 in total