Clostridium botulinum strain RF5

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium botulinum strain RF5 is a Gram-positive, rod-shaped bacterium known for its role as a significant human pathogen. This anaerobic organism thrives in multiple habitats and is categorized as a chemoorganotroph, utilizing organic compounds as an energy source. C. botulinum RF5 is capable of mobility, possessing flagella that enable movement. The strain typically exists in various arrangements, including pairs, singles, and chains. It has a mesophilic temperature range, with an optimal growth temperature of 37 degrees Celsius. Notably, this bacterium has a single replicon and one membrane, characteristics that contribute to its cellular structure and function. C. botulinum RF5 is notably associated with health effects such as wound botulism and botulism, which result from the production of botulinum toxin. The biotic relationship of this strain is classified as free living, indicating that it does not depend on a host for survival, although it can affect Homo sapiens. The ecological insight from the presence of C. botulinum RF5 lies in its ability to thrive in anaerobic environments, which are often found in decaying organic matter. This adaptability highlights the bacterium's role in nutrient cycling within ecosystems, even as it poses significant risks to human health through toxin production. Understanding the ecology and behavior of C. botulinum RF5 is crucial in managing its impacts on both health and the environment.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium botulinum
Strainstrain RF5

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium botulinum strain RF5
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Metazoa
Cell arrangementPairs - Singles - Chains
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Clostridium botulinum strain RF5 chromosome, complete genome.

Gene Summary

Adenine Count

1416430 bp

Thymine Count

1471138 bp

Guanine Count

537670 bp

Cytosine Count

573509 bp

Genome Length

3998747 bp

Protein-coding Genes

3614 genes

Non-Coding Genes

109 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
gnat family n-acetyltransferaseC7M58_RS14895Not AvailableNegative3188562 - 318901717909.7
hypothetical proteinC7M58_RS14900Not AvailableNegative3189275 - 319002428598.9
abc transporter atp-binding proteinC7M58_RS14905Not AvailableNegative3190025 - 319089733124.4
gntr family transcriptional regulatorC7M58_RS14910Not AvailableNegative3190890 - 319126114051.0
sensor histidine kinaseC7M58_RS14915Not AvailableNegative3191537 - 319255039387.6
response regulator transcription factorC7M58_RS14920Not AvailableNegative3192550 - 319322726492.7
abc transporter permeaseC7M58_RS14925Not AvailableNegative3193381 - 319585293147.9
abc transporter atp-binding proteinC7M58_RS14930Not AvailableNegative3195836 - 319652525026.4
tyrosine--trna ligaseC7M58_RS14935Not AvailableNegative3196815 - 319801745631.2
family 14 glycosylhydrolaseC7M58_RS14940Not AvailableNegative3198786 - 320041462030.5

Displaying genes 2931 – 2940 of 3723 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Wound botulismCausesPMC8283217
BotulismCausesPMC2693436
BotulismCausesPMC13317340
BotulismCausesPMC3232984
BotulismCausesPMC5113727
BotulismCausesPMC7904509

Displaying health effects 1 – 6 of 6 in total