Klebsiella pneumoniae strain NUHL30457

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain NUHL30457 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain is capable of thriving in the presence or absence of oxygen, which allows it to adapt to various environmental conditions. It typically exists in chains, pairs, or as single cells and exhibits mobility due to the presence of flagella. The optimal growth temperature for NUHL30457 is 37°C, indicating it is mesophilic and well-suited to the human body and other warm-blooded hosts. The strain harbors five replicons and has a double membrane structure, which is characteristic of Gram-negative bacteria. It has been isolated from a wide range of hosts, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae, highlighting its versatility and adaptability in different ecological niches. Klebsiella pneumoniae NUHL30457 is associated with several serious health effects, including bacteremia, urinary tract infections, pneumonia, and various other infections such as meningitis and sepsis. Its pathogenicity is primarily directed towards humans, but its presence in multiple host species indicates a broader ecological role. This adaptability and range of pathogenic effects underscore the importance of monitoring Klebsiella pneumoniae in clinical settings, as it poses significant risks to human health and can lead to severe infections in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain NUHL30457

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain NUHL30457
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain NUHL30457


Gene Summary

Adenine Count

21035 bp

Thymine Count

20682 bp

Guanine Count

24277 bp

Cytosine Count

23253 bp

Genome Length

89247 bp

Protein-coding Genes

89 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Antirestriction proteinC3483_RS29120Not AvailableNegative62887 - 6339319618.0
hypothetical proteinC3483_RS29125Not AvailableNegative63798 - 6457729169.0
duf1380 family proteinC3483_RS29130Not AvailableNegative64631 - 6505015445.5
Gp50C3483_RS29135Not AvailableNegative65061 - 652828492.17
Dna methylaseC3483_RS29140Not AvailableNegative65282 - 6595925264.2
Sos response associated peptidaseC3483_RS29145Not AvailablePositive66318 - 6698925389.7
Protein umudC3483_RS29150Not AvailablePositive67169 - 6759115467.8
Dna polymeraseC3483_RS29155Not AvailablePositive67591 - 6886247583.3
Partition protein parbC3483_RS29165Not AvailableNegative68998 - 6996936435.8
Partition protein paraC3483_RS29170Not AvailableNegative69966 - 7117145104.1

Displaying genes 41 – 50 of 5797 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total