Klebsiella pneumoniae strain NUHL30457

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain NUHL30457 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain is capable of thriving in the presence or absence of oxygen, which allows it to adapt to various environmental conditions. It typically exists in chains, pairs, or as single cells and exhibits mobility due to the presence of flagella. The optimal growth temperature for NUHL30457 is 37°C, indicating it is mesophilic and well-suited to the human body and other warm-blooded hosts. The strain harbors five replicons and has a double membrane structure, which is characteristic of Gram-negative bacteria. It has been isolated from a wide range of hosts, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae, highlighting its versatility and adaptability in different ecological niches. Klebsiella pneumoniae NUHL30457 is associated with several serious health effects, including bacteremia, urinary tract infections, pneumonia, and various other infections such as meningitis and sepsis. Its pathogenicity is primarily directed towards humans, but its presence in multiple host species indicates a broader ecological role. This adaptability and range of pathogenic effects underscore the importance of monitoring Klebsiella pneumoniae in clinical settings, as it poses significant risks to human health and can lead to severe infections in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain NUHL30457

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain NUHL30457
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain NUHL30457 plasmid p3, complete

Gene Summary

Adenine Count

21035 bp

Thymine Count

20682 bp

Guanine Count

24277 bp

Cytosine Count

23253 bp

Genome Length

89247 bp

Protein-coding Genes

89 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
23s rrna (uracil(1939)-c(5))-methyltransferase rlmdC3483_RS05185Not AvailablePositive1030540 - 103184448530.7
gtp diphosphokinaseC3483_RS05190Not AvailablePositive1031966 - 103420384173.7
nucleoside triphosphate pyrophosphohydrolaseC3483_RS05195Not AvailablePositive1034316 - 103510730148.7
glutamine hydrolyzing ctp synthaseC3483_RS05200Not AvailablePositive1035388 - 103702560166.4
phosphopyruvate hydrataseC3483_RS05205Not AvailablePositive1037107 - 103840545552.3
sdr family oxidoreductaseC3483_RS05210Not AvailableNegative1038470 - 103957941278.5
7-carboxy-7-deazaguanine synthase queeC3483_RS05215Not AvailablePositive1040054 - 104072524996.9
6-carboxytetrahydropterin synthase quedC3483_RS05220Not AvailableNegative1040766 - 104113113860.7
nadph-dependent assimilatory sulfite reductase flavoprotein subunitC3483_RS05225Not AvailablePositive1041448 - 104324766053.0
assimilatory sulfite reductase (nadph) hemoprotein subunitC3483_RS05230Not AvailablePositive1043247 - 104495964052.8

Displaying genes 1421 – 1430 of 5797 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total