Helicobacter pylori strain dRdM2addM2

Helicobacter pylori strain dRdM2addM2 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella, which contribute to its motility. This strain is primarily host-associated, with Homo sapiens being a significant host, alongside other species such as Gallus gallus, various birds (Aves), primates, and rodents (Rodentia, Cricetinae). It is classified as free-living within its host environments. The optimal growth temperature for strain dRdM2addM2 is 37°C, placing it within the mesophilic temperature range. This organism has a single replicon and consists of two membranes, typical of Gram-negative bacteria. Helicobacter pylori is well-known for its pathogenic effects on human health, being linked to various gastrointestinal diseases. The strain dRdM2addM2 is associated with chronic gastric inflammation, gastric ulcers, and more severe conditions such as gastric cancer and mucosa-associated lymphoid tissue lymphoma. Other health impacts include functional dyspepsia, atrophic gastritis, and peptic ulcer disease. The ecological insight derived from the presence of H. pylori within diverse hosts indicates its adaptability and potential role in complex host-microbiome interactions. This adaptability could influence the development of gastrointestinal diseases, highlighting the importance of understanding H. pylori's biology and pathogenicity in both human and animal health contexts. The accessions for this strain can be found under NZ_CP026515.1.