Akkermansia muciniphila strain EB-AMDK-18

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain EB-AMDK-18 is a Gram-negative, non-motile coccus that thrives in anaerobic environments. This strain is primarily associated with host organisms, specifically Homo sapiens and other Metazoa. Its optimal growth temperature is 37°C, classifying it as mesophilic within a temperature range suited for human body conditions. The organism is characterized by a unique cell arrangement, typically found in singles or pairs, and possesses a double membrane structure. Notably, Akkermansia muciniphila strain EB-AMDK-18 does not form spores, indicating a continuous mode of growth rather than a survival strategy in harsh conditions. This strain is known to have significant implications for human health, being associated with food allergies and the thinning of the jejunum mucus layer. These health effects suggest a complex biotic relationship with the host, wherein the presence or absence of this bacterium could influence gut health and immune responses. The strain's free-living nature indicates it can thrive independently, yet it plays a critical role in the host's microbiome. In conclusion, Akkermansia muciniphila strain EB-AMDK-18 exemplifies the intricate relationship between gut microbiota and host health. Its specific traits underscore its potential as a key player in maintaining gut barrier integrity and influencing host immune functions. Further study of this strain may provide insights into its role in health and disease, particularly concerning digestive health and immune responses.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain EB-AMDK-18

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain EB-AMDK-18
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain EB-AMDK-18 chromosome, complete

Gene Summary

Adenine Count

618995 bp

Thymine Count

619226 bp

Guanine Count

768563 bp

Cytosine Count

763340 bp

Genome Length

2770124 bp

Protein-coding Genes

2311 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcription termination factor rhoC1O57_RS03885Not AvailableNegative918367 - 92034673614.4
yebc/pmpr family dna-binding transcriptional regulatorC1O57_RS03890Not AvailableNegative920398 - 92115326927.5
cation diffusion facilitator family transporterC1O57_RS03895Not AvailablePositive921690 - 92312053039.2
cation:proton antiporterC1O57_RS03900Not AvailableNegative923227 - 92497261776.7
hypothetical proteinC1O57_RS03905Not AvailablePositive925490 - 92615226123.9
trna preq1(34) s-adenosylmethionine ribosyltransferase-isomerase queaC1O57_RS03910Not AvailableNegative926211 - 92720037537.3
flotillin-like protein floaC1O57_RS03915Not AvailablePositive927295 - 92834437100.9
hypothetical proteinC1O57_RS03920Not AvailablePositive928396 - 92904624051.7
thiazole synthaseC1O57_RS03925Not AvailablePositive929153 - 92993527015.8
apc family permeaseC1O57_RS03930Not AvailableNegative929977 - 93128146280.1

Displaying genes 791 – 800 of 2376 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total