Prevotella intermedia strain KCOM 1933

Prevotella intermedia strain KCOM 1933 is a Gram-negative, anaerobic bacterium characterized by its rod shape and the presence of flagella. This strain is notably found in diverse habitats within the human body, including the gingival sulci, oral cavity, gut, subgingival and supragingival dental biofilms, and the urogenital tract. It is also present in subgingival plaque, where it plays a role in the complex microbial community associated with periodontal health and disease. Prevotella intermedia is primarily associated with various health effects, particularly those related to oral and systemic infections. It has been implicated in conditions such as periodontal disease, dental caries, and periapical periodontitis, as well as more severe complications like intracranial infections and noma. Its pathogenicity in humans highlights its significance in dental health and the potential consequences of dysbiosis within the oral microbiome. The strain KCOM 1933 is characterized by having two replicons, which may contribute to its adaptability in different environments within the host. Understanding the ecological roles and health implications of Prevotella intermedia KCOM 1933 is vital, particularly in the context of oral health, as it underscores the delicate balance of microbial communities and their influence on both local and systemic health outcomes.