Prevotella intermedia strain KCOM 2033

Prevotella intermedia strain KCOM 2033 is a Gram-negative, rod-shaped bacterium that primarily thrives in anaerobic environments. This strain is notably found in various habitats within the human body, including the gingival sulci, oral cavity, gut, subgingival and supragingival dental biofilms, subgingival plaque, and the urogenital tract. The presence of flagella enables motility, which may contribute to its ability to colonize these diverse niches. P. intermedia is recognized for its pathogenic potential in humans, associated with several health complications such as periodontal disease, dental caries, periapical periodontitis, periodontal abscesses, and noma. Additionally, it has been linked to more severe conditions, including intracranial infections. These health effects highlight the bacterium's role in oral and systemic diseases, emphasizing its significance in dental and medical microbiology. The strain KCOM 2033 possesses a single replicon, indicating a streamlined genomic structure that may facilitate its adaptability and survival in the complex microbial ecosystems of the human body. The ability to colonize multiple habitats, particularly within the oral cavity and its association with periodontal diseases, suggests that P. intermedia plays a crucial role in the dynamics of oral health and disease. Understanding its behavior and interactions in these environments can provide insights into the management and prevention of periodontal diseases and their systemic implications.