Helicobacter pylori strain 7.13_D1b

Helicobacter pylori strain 7.13_D1b is a gram-negative bacterium that exhibits a spiral shape and is classified as microaerophilic, thriving in environments with limited oxygen. This strain is characterized by its single-cell arrangement and the presence of flagella, which may aid in its motility despite being noted as non-motile. It has a mesophilic temperature range with an optimal growth temperature of 37°C. The strain is predominantly host-associated, with a diverse array of hosts including Homo sapiens, Gallus gallus, various Aves, Primates, Mammalia, Amoeba, Rodentia, Cricetinae, and Thais. This wide host range highlights its adaptability and ecological versatility. Helicobacter pylori strain 7.13_D1b is known for its pathogenicity in humans, being associated with several significant health issues. These include chronic gastric inflammation, peptic ulcer disease, and various forms of gastric cancer, such as gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. The bacterium is linked to conditions like gastritis, GERD, and functional dyspepsia, indicating its role in gastrointestinal diseases. The strain has a single replicon and two membranes, typical of Gram-negative bacteria, which may contribute to its pathogenic mechanisms and interactions with host tissues. Given its significant health impacts, understanding the biology and ecology of Helicobacter pylori strain 7.13_D1b is essential for addressing its role in gastrointestinal diseases and potential therapeutic interventions.