Mycobacterium intracellulare strain FLAC0181

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium intracellulare strain FLAC0181 is a notable bacterium characterized by the presence of flagella and a single replicon. This strain is primarily associated with hosts including Homo sapiens and other Metazoa. It is recognized for its health implications, particularly concerning pulmonary disease. In humans, M. intracellulare can cause non-tuberculous mycobacterial (NTM) lung disease, potentially leading to disseminated disease and localized lesions. The presence of flagella in this strain may play a role in its pathogenicity, as flagella can contribute to bacterial motility and colonization in host tissues. The single replicon indicates a streamlined genetic structure, which is typical for many mycobacterial species, allowing for effective replication and adaptation to various environments, including those within host organisms. Overall, the traits of Mycobacterium intracellulare strain FLAC0181 highlight its potential as a significant pathogen in pulmonary diseases, particularly among individuals with compromised immune systems. Understanding its characteristics and interactions with hosts can provide insights into its ecological role and the mechanisms of NTM lung disease. Given the increasing recognition of non-tuberculous mycobacteria as opportunistic pathogens, further research into strains like FLAC0181 is essential for developing appropriate treatment strategies. The accession number for this strain is NZ_CP023149.1, which can be referenced for genomic data and further insights into its characteristics.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium intracellulare
Strainstrain FLAC0181

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Mycobacterium intracellulare strain FLAC0181


Gene Summary

Adenine Count

897208 bp

Thymine Count

902990 bp

Guanine Count

1907886 bp

Cytosine Count

1905857 bp

Genome Length

5613941 bp

Protein-coding Genes

5198 genes

Non-Coding Genes

62 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uracil-dna glycosylaseCKJ67_RS18795Not AvailableNegative4038903 - 403958624472.5
thiamine-phosphate kinaseCKJ67_RS18800Not AvailableNegative4039628 - 404057532237.0
duf3515 domain-containing proteinCKJ67_RS18805Not AvailablePositive4040621 - 404120520154.1
d-alanine--d-alanine ligase family proteinCKJ67_RS18810Not AvailableNegative4041206 - 404235140173.9
nad(p)h-dependent glycerol-3-phosphate dehydrogenaseCKJ67_RS18815Not AvailableNegative4042383 - 404342635243.5
2-phospho-l-lactate guanylyltransferaseCKJ67_RS18820Not AvailablePositive4043582 - 404423221868.0
rna degradosome polyphosphate kinaseCKJ67_RS18825Not AvailablePositive4044431 - 404663282162.0
nudix hydrolaseCKJ67_RS18830Not AvailablePositive4046717 - 404766434350.8
hu family dna-binding proteinCKJ67_RS18835Not AvailableNegative4047783 - 404843022255.5
3-isopropylmalate dehydratase small subunitCKJ67_RS18840Not AvailableNegative4048642 - 404923821895.9

Displaying genes 3731 – 3740 of 5260 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Pulmonary diseaseCausesPMC12584685
Pulmonary diseaseCausesPMC7840607
Pulmonary diseaseCausesPMC5759224
Disseminated diseaseCausesPMC5759224
Localized lesionsCausesPMC5759224
Ntm lung diseaseCausesPMC6031696

Displaying health effects 1 – 6 of 6 in total