Mycobacterium intracellulare strain FLAC0181

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium intracellulare strain FLAC0181 is a notable bacterium characterized by the presence of flagella and a single replicon. This strain is primarily associated with hosts including Homo sapiens and other Metazoa. It is recognized for its health implications, particularly concerning pulmonary disease. In humans, M. intracellulare can cause non-tuberculous mycobacterial (NTM) lung disease, potentially leading to disseminated disease and localized lesions. The presence of flagella in this strain may play a role in its pathogenicity, as flagella can contribute to bacterial motility and colonization in host tissues. The single replicon indicates a streamlined genetic structure, which is typical for many mycobacterial species, allowing for effective replication and adaptation to various environments, including those within host organisms. Overall, the traits of Mycobacterium intracellulare strain FLAC0181 highlight its potential as a significant pathogen in pulmonary diseases, particularly among individuals with compromised immune systems. Understanding its characteristics and interactions with hosts can provide insights into its ecological role and the mechanisms of NTM lung disease. Given the increasing recognition of non-tuberculous mycobacteria as opportunistic pathogens, further research into strains like FLAC0181 is essential for developing appropriate treatment strategies. The accession number for this strain is NZ_CP023149.1, which can be referenced for genomic data and further insights into its characteristics.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium intracellulare
Strainstrain FLAC0181

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Mycobacterium intracellulare strain FLAC0181


Gene Summary

Adenine Count

897208 bp

Thymine Count

902990 bp

Guanine Count

1907886 bp

Cytosine Count

1905857 bp

Genome Length

5613941 bp

Protein-coding Genes

5198 genes

Non-Coding Genes

62 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fad-dependent monooxygenaseCKJ67_RS27110Not AvailableNegative2372837 - 237355326328.0
nad(p)-binding proteinCKJ67_RS27115Not AvailableNegative2373472 - 237395717063.2
tetr/acrr family transcriptional regulatorCKJ67_RS11375Not AvailablePositive2374029 - 237463422261.8
udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2, 6-diaminopimelate ligaseCKJ67_RS11380Not AvailablePositive2374700 - 237626853292.4
udp-n-acetylmuramoyl-tripeptide--d-alanyl-d- alanine ligaseCKJ67_RS11385Not AvailablePositive2376265 - 237781251662.5
phospho-n-acetylmuramoyl-pentapeptide- transferaseCKJ67_RS11390Not AvailablePositive2377809 - 237888837624.3
udp-n-acetylmuramoyl-l-alanine--d-glutamate ligaseCKJ67_RS11395Not AvailablePositive2378888 - 238034548887.4
putative lipid ii flippase ftswCKJ67_RS11400Not AvailablePositive2380354 - 238205159985.2
undecaprenyldiphospho-muramoylpentapeptide beta-n-acetylglucosaminyltransferaseCKJ67_RS11405Not AvailablePositive2382048 - 238326541222.9
udp-n-acetylmuramate--l-alanine ligaseCKJ67_RS11410Not AvailablePositive2383262 - 238474051082.1

Displaying genes 2281 – 2290 of 5260 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Pulmonary diseaseCausesPMC12584685
Pulmonary diseaseCausesPMC7840607
Pulmonary diseaseCausesPMC5759224
Disseminated diseaseCausesPMC5759224
Localized lesionsCausesPMC5759224
Ntm lung diseaseCausesPMC6031696

Displaying health effects 1 – 6 of 6 in total