Corynebacterium jeikeium strain FDAARGOS_328

Gram-positiveRodNon-motileFacultative aerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Corynebacterium jeikeium strain FDAARGOS_328 is a gram-positive, rod-shaped bacterium that demonstrates a facultative aerobic metabolism, functioning as a chemoorganotroph. This organism is characterized by its single-cell arrangement and lacks mobility, as it does not possess flagella. C. jeikeium is mesophilic, thriving within a temperature range typical of human body temperatures, which facilitates its opportunistic pathogenicity. Notably, this strain has been associated with a variety of serious health complications in humans, including pneumonia, endocarditis, peritonitis, meningitis, wound infections, osteomyelitis, sepsis, septicemia, conjunctivitis, keratitis, skin lesions, soft tissue infections, and infections related to hemodialysis catheters and joint infections. The ecological role of C. jeikeium is primarily free-living, and it resides in multiple habitats. However, its significant biotic relationship with humans highlights its potential as an opportunistic pathogen, particularly in immunocompromised individuals. The presence of a single replicon and a single membrane indicates a relatively simple cellular structure, which may contribute to its adaptability within various environments. Given its broad spectrum of infections and association with healthcare settings, understanding the behavior and characteristics of C. jeikeium is essential for managing its clinical implications effectively. The strain's accession number is NZ_CP022054.2, providing a reference for further genetic and biochemical studies.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium jeikeium
Strainstrain FDAARGOS_328

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Corynebacterium jeikeium strain FDAARGOS_328
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative aerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Corynebacterium jeikeium strain FDAARGOS_328 chromosome, complete

Gene Summary

Adenine Count

547597 bp

Thymine Count

548565 bp

Guanine Count

778867 bp

Cytosine Count

775849 bp

Genome Length

2650878 bp

Protein-coding Genes

2225 genes

Non-Coding Genes

128 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cytochrome d ubiquinol oxidase subunit iiCEQ06_RS18565Not AvailablePositive1481266 - 148228237179.0
abc transporter atp-binding protein/permeaseCEQ06_RS18570Not AvailablePositive1482312 - 148386254587.3
thiol reductant abc exporter subunit cydcCEQ06_RS18575Not AvailablePositive1483859 - 148559861130.1
trna dihydrouridine synthase dusbCEQ06_RS18580Not AvailablePositive1485731 - 148688841860.8
phosphate signaling complex protein phouCEQ06_RS18585Not AvailablePositive1486979 - 148771628282.5
phosphate abc transporter atp-binding protein pstbCEQ06_RS18590Not AvailableNegative1488168 - 148894428261.9
phosphate abc transporter permease pstaCEQ06_RS18595Not AvailableNegative1488993 - 148988631842.1
phosphate abc transporter permease subunit pstcCEQ06_RS18600Not AvailableNegative1489964 - 149100736653.2
phosphate abc transporter substrate-binding protein pstsCEQ06_RS18605Not AvailableNegative1491244 - 149230537255.3
mycothiol synthaseCEQ06_RS18610Not AvailableNegative1492683 - 149359132952.6

Displaying genes 1341 – 1350 of 2353 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Wound infectionsCausesPMC12505879
SepsisCausesPMC12505879
EndocarditisCausesPMC12505879
SepticemiaCausesPMC12505879
PneumoniaCausesPMC12505879
PeritonitisCausesPMC12505879
OsteomyelitisCausesPMC12505879
MeningitisCausesPMC12505879
Infections of hemodialysis cathetersCausesPMC12505879
Soft tissue infectionCausesPMC12505879

Displaying health effects 1 – 10 of 24 in total