Acinetobacter baumannii strain A85

Gram-negativeRodNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Moraxellales

Family

Moraxellaceae

Genus

Acinetobacter

Description

Acinetobacter baumannii strain A85 is a notable Gram-negative bacterium characterized by its rod shape and aerobic metabolism. This strain is classified as a chemoheterotroph, relying on organic compounds for energy. A85 exhibits a free-living biotic relationship and does not possess mobility, as it is non-flagellated. It thrives optimally at 37°C and is categorized as mesophilic, indicating its preference for moderate temperature environments. The strain has a complex genetic structure, containing five replicons and two membranes, which may contribute to its adaptability and survival in diverse habitats. Acinetobacter baumannii strain A85 is of significant concern in clinical settings due to its pathogenicity in humans, where it is associated with a variety of severe health effects. These include bacteremia, necrotizing fasciitis, bloodstream infections, urinary tract infections, and nosocomial infections such as hospital-acquired pneumonia. A85 is also implicated in traumatic injuries and respiratory tract infections, highlighting its potential to cause community-acquired infections as well. The prevalence of A. baumannii in healthcare environments raises critical concerns about its role in healthcare-associated infections. Its ability to persist in multiple habitats and cause a wide range of infections underscores the importance of monitoring and understanding this strain to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderMoraxellales
FamilyMoraxellaceae
GenusAcinetobacter
SpeciesAcinetobacter baumannii
Strainstrain A85

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Acinetobacter baumannii strain A85
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementSingles
SporulationNot Available
Energy sourceHeterotroph - Chemoheterotroph
PathogenicityHuman

Genome Summary

Acinetobacter baumannii strain A85 plasmid pA85-2, complete

Gene Summary

Adenine Count

3047 bp

Thymine Count

2683 bp

Guanine Count

1495 bp

Cytosine Count

1506 bp

Genome Length

8731 bp

Protein-coding Genes

11 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multidrug efflux rnd transporter periplasmic adaptor subunit adeaCBI29_RS10315Not AvailableNegative2114580 - 211577043373.9
efflux system response regulator transcription factor aderCBI29_RS10320Not AvailablePositive2115916 - 211665928355.4
two-component sensor histidine kinase adesCBI29_RS10325Not AvailablePositive2116691 - 211777640773.7
hypothetical proteinCBI29_RS10330Not AvailableNegative2117802 - 211821515599.1
arac family transcriptional regulatorCBI29_RS10335Not AvailableNegative2118297 - 211932239662.6
alpha/beta hydrolaseCBI29_RS10340Not AvailablePositive2119514 - 212042833280.2
sdr family nad(p)-dependent oxidoreductaseCBI29_RS10345Not AvailablePositive2120459 - 212131930994.7
sdr family nad(p)-dependent oxidoreductaseCBI29_RS10350Not AvailablePositive2121365 - 212220730508.2
lysr family transcriptional regulatorCBI29_RS10355Not AvailableNegative2122303 - 212320233913.1
alpha/beta hydrolaseCBI29_RS10360Not AvailablePositive2123313 - 212423633503.5

Displaying genes 2251 – 2260 of 3937 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Hospital-acquired pneumoniaCausesPMC11264759
BacteremiaCausesPMC11264759
Urinary tract infectionsCausesPMC11264759
Traumatic injuriesCausesPMC11264759
Respiratory tract infectionCausesPMC11514839
Healthcare-associated infectionsCausesPMC13168211
BacteremiaCausesPMC10561989
Hospital-acquired pneumoniaCausesPMC11925754
Bloodstream infectionsCausesPMC11925754
Wound contaminationsCausesPMC11925754

Displaying health effects 1 – 10 of 17 in total