Bifidobacterium breve strain NRBB57

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve strain NRBB57 is a Gram-positive, anaerobic bacterium characterized by its rod shape and the presence of flagella. This strain is primarily found in the gastrointestinal tract, specifically within the gut microbiota of healthy newborns, and is notably present in human breast milk. Its habitat includes the intestines of infants, where it plays a crucial role in the development of the gut microbiome. Bifidobacterium breve is nonsporulating and has a single replicon, indicating a stable genomic structure that may contribute to its adaptability in the infant gut environment. The presence of this strain in breast milk highlights its importance in early nutrition and the establishment of a healthy microbiota in newborns. The ecological role of Bifidobacterium breve NRBB57 in the infant intestine is significant as it is associated with promoting gut health and potentially influencing immune system development. By colonizing the gut, this bacterium can help in the digestion of complex carbohydrates, producing beneficial short-chain fatty acids that support overall gut function and health. The presence of Bifidobacterium breve in the microbiota of healthy newborns suggests its vital contribution to the establishment of a balanced gut ecosystem during the critical early stages of life.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strainstrain NRBB57

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve strain NRBB57
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain NRBB57 chromosome, complete genome.

Gene Summary

Adenine Count

511257 bp

Thymine Count

508565 bp

Guanine Count

743115 bp

Cytosine Count

747444 bp

Genome Length

2510381 bp

Protein-coding Genes

2149 genes

Non-Coding Genes

103 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphoribosylformylglycinamidine synthaseNRBB57_RS02800Not AvailableNegative667498 - 671232134305.0
phosphoribosylaminoimidazolesuccinocarboxamide synthaseNRBB57_RS02805Not AvailableNegative671440 - 67219228247.9
formate-dependent phosphoribosylglycinamide formyltransferaseNRBB57_RS02810Not AvailableNegative672274 - 67357545233.8
pyridoxal phosphate-dependent aminotransferaseNRBB57_RS02815Not AvailablePositive674072 - 67532243332.0
glycosyltransferaseNRBB57_RS02820Not AvailablePositive675439 - 67659942712.7
threonine aldolase family proteinNRBB57_RS02825Not AvailableNegative676712 - 67773737403.0
Trna-hisNot AvailableNot AvailablePositive677845 - 677920Not Available
glycoside hydrolase family 3 n-terminal domain-containing proteinNRBB57_RS02835Not AvailablePositive678152 - 67880223327.6
30s ribosomal protein s12NRBB57_RS02845Not AvailablePositive679386 - 67975713565.8
30s ribosomal protein s7NRBB57_RS02850Not AvailablePositive679763 - 68023317554.2

Displaying genes 571 – 580 of 2252 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.