Bifidobacterium breve strain NRBB57

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve strain NRBB57 is a Gram-positive, anaerobic bacterium characterized by its rod shape and the presence of flagella. This strain is primarily found in the gastrointestinal tract, specifically within the gut microbiota of healthy newborns, and is notably present in human breast milk. Its habitat includes the intestines of infants, where it plays a crucial role in the development of the gut microbiome. Bifidobacterium breve is nonsporulating and has a single replicon, indicating a stable genomic structure that may contribute to its adaptability in the infant gut environment. The presence of this strain in breast milk highlights its importance in early nutrition and the establishment of a healthy microbiota in newborns. The ecological role of Bifidobacterium breve NRBB57 in the infant intestine is significant as it is associated with promoting gut health and potentially influencing immune system development. By colonizing the gut, this bacterium can help in the digestion of complex carbohydrates, producing beneficial short-chain fatty acids that support overall gut function and health. The presence of Bifidobacterium breve in the microbiota of healthy newborns suggests its vital contribution to the establishment of a balanced gut ecosystem during the critical early stages of life.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strainstrain NRBB57

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve strain NRBB57
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain NRBB57 chromosome, complete genome.

Gene Summary

Adenine Count

511257 bp

Thymine Count

508565 bp

Guanine Count

743115 bp

Cytosine Count

747444 bp

Genome Length

2510381 bp

Protein-coding Genes

2149 genes

Non-Coding Genes

103 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter permeaseNRBB57_RS02645Not AvailablePositive638246 - 63977554182.2
1-deoxy-d-xylulose-5-phosphate synthaseNRBB57_RS02650Not AvailableNegative639759 - 64180172070.9
zinc-binding dehydrogenaseNRBB57_RS02655Not AvailablePositive642064 - 64305634453.1
5-(carboxyamino)imidazole ribonucleotide mutaseNRBB57_RS02660Not AvailablePositive643123 - 64362317496.1
5-(carboxyamino)imidazole ribonucleotide synthaseNRBB57_RS02665Not AvailablePositive643607 - 64478542880.8
fur family transcriptional regulatorNRBB57_RS02670Not AvailablePositive644794 - 64522215801.7
abc transporter permeaseNRBB57_RS02675Not AvailableNegative645269 - 64599126423.1
hypothetical proteinNRBB57_RS02680Not AvailableNegative645976 - 64639515366.2
glycoside hydrolase family 3 n-terminal domain-containing proteinNRBB57_RS02685Not AvailableNegative646401 - 64684416213.5
tetr-like c-terminal domain-containing proteinNRBB57_RS02690Not AvailablePositive646848 - 64715011472.0

Displaying genes 541 – 550 of 2252 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.