Bifidobacterium breve strain NRBB57

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve strain NRBB57 is a Gram-positive, anaerobic bacterium characterized by its rod shape and the presence of flagella. This strain is primarily found in the gastrointestinal tract, specifically within the gut microbiota of healthy newborns, and is notably present in human breast milk. Its habitat includes the intestines of infants, where it plays a crucial role in the development of the gut microbiome. Bifidobacterium breve is nonsporulating and has a single replicon, indicating a stable genomic structure that may contribute to its adaptability in the infant gut environment. The presence of this strain in breast milk highlights its importance in early nutrition and the establishment of a healthy microbiota in newborns. The ecological role of Bifidobacterium breve NRBB57 in the infant intestine is significant as it is associated with promoting gut health and potentially influencing immune system development. By colonizing the gut, this bacterium can help in the digestion of complex carbohydrates, producing beneficial short-chain fatty acids that support overall gut function and health. The presence of Bifidobacterium breve in the microbiota of healthy newborns suggests its vital contribution to the establishment of a balanced gut ecosystem during the critical early stages of life.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strainstrain NRBB57

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve strain NRBB57
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain NRBB57 chromosome, complete genome.

Gene Summary

Adenine Count

511257 bp

Thymine Count

508565 bp

Guanine Count

743115 bp

Cytosine Count

747444 bp

Genome Length

2510381 bp

Protein-coding Genes

2149 genes

Non-Coding Genes

103 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alpha-amylase family glycosyl hydrolaseNRBB57_RS00615Not AvailableNegative160648 - 16246267150.8
laci family dna-binding transcriptional regulatorNRBB57_RS00620Not AvailableNegative162734 - 16376536480.4
spaa isopeptide-forming pilin-related proteinNRBB57_RS00630Not AvailablePositive164676 - 169088155069.0
isopeptide-forming domain-containing fimbrial proteinNRBB57_RS00635Not AvailablePositive169193 - 17102864662.1
class c sortaseNRBB57_RS00640Not AvailablePositive171285 - 17224434795.9
4-alpha-glucanotransferaseNRBB57_RS00645Not AvailableNegative172560 - 17476481098.7
alpha-amylase family glycosyl hydrolaseNRBB57_RS00650Not AvailableNegative175021 - 17690769773.4
extracellular solute-binding proteinNRBB57_RS00655Not AvailablePositive177164 - 17840543915.7
carbohydrate abc transporter permeaseNRBB57_RS00660Not AvailablePositive178772 - 18014551500.6
sugar abc transporter permeaseNRBB57_RS00665Not AvailablePositive180181 - 18106233148.8

Displaying genes 151 – 160 of 2252 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.