Escherichia coli strain 95NR1

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 95NR1 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. It can be found in pairs or singles and possesses flagella, granting it mobility. This strain thrives at an optimal temperature of 37°C and falls within the mesophilic temperature range. Notably, it contains three replicons and is characterized by a double membrane structure. The ecological niche of E. coli strain 95NR1 is primarily host-associated, indicating its reliance on various hosts for survival and propagation. It has been identified in a diverse range of hosts, including Homo sapiens, Gallus gallus, and numerous other animals, plants, and invertebrates. This extensive list of hosts underscores its adaptability and ecological versatility. In terms of health implications, E. coli strain 95NR1 is associated with a multitude of pathogenic effects in humans, such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and foodborne illnesses. It has also been linked to more severe conditions like hemolytic uremic syndrome (HUS), septicemia, and various inflammatory diseases. The strain's ability to inhabit multiple hosts and its pathogenic potential highlight its role in both environmental and clinical settings. This adaptability may facilitate the transmission of antibiotic resistance and other virulence factors among different species, posing a significant challenge for public health and necessitating ongoing monitoring and research into its ecological impact and pathogenic mechanisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 95NR1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 95NR1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence.

Gene Summary

Adenine Count

22646 bp

Thymine Count

22762 bp

Guanine Count

20666 bp

Cytosine Count

20843 bp

Genome Length

86917 bp

Protein-coding Genes

5 genes

Non-Coding Genes

100 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
isncy family transposaseEC95NR1_RS14930Not AvailablePositive2757249 - 275815134902.7
helix-turn-helix transcriptional regulatorEC95NR1_RS14935Not AvailableNegative2758192 - 275865316341.5
nicotinamide mononucleotide deamidase-related protein yfayEC95NR1_RS14940Not AvailableNegative2758717 - 275991944260.3
yfaz family outer membrane proteinEC95NR1_RS14945Not AvailableNegative2760019 - 276056118596.8
nucleoside triphosphatase nudiEC95NR1_RS14950Not AvailablePositive2760840 - 276126516361.6
lipopolysaccharide core heptose(ii)-phosphate phosphatase aisEC95NR1_RS14955Not AvailableNegative2761304 - 276190622290.8
udp-4-amino-4-deoxy-l-arabinose aminotransferaseEC95NR1_RS14960Not AvailablePositive2762214 - 276335341674.2
undecaprenyl-phosphate 4-deoxy-4-formamido-l-arabinose transferaseEC95NR1_RS14965Not AvailablePositive2763357 - 276432536357.3
bifunctional udp-4-amino-4-deoxy-l-arabinose formyltransferase/udp-glucuronic acid oxidase arnaEC95NR1_RS14970Not AvailablePositive2764325 - 276630774234.0
4-deoxy-4-formamido-l-arabinose- phosphoundecaprenol deformylaseEC95NR1_RS14975Not AvailablePositive2766304 - 276719433113.6

Displaying genes 3451 – 3460 of 5812 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total