Escherichia coli strain 95NR1

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 95NR1 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. It can be found in pairs or singles and possesses flagella, granting it mobility. This strain thrives at an optimal temperature of 37°C and falls within the mesophilic temperature range. Notably, it contains three replicons and is characterized by a double membrane structure. The ecological niche of E. coli strain 95NR1 is primarily host-associated, indicating its reliance on various hosts for survival and propagation. It has been identified in a diverse range of hosts, including Homo sapiens, Gallus gallus, and numerous other animals, plants, and invertebrates. This extensive list of hosts underscores its adaptability and ecological versatility. In terms of health implications, E. coli strain 95NR1 is associated with a multitude of pathogenic effects in humans, such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and foodborne illnesses. It has also been linked to more severe conditions like hemolytic uremic syndrome (HUS), septicemia, and various inflammatory diseases. The strain's ability to inhabit multiple hosts and its pathogenic potential highlight its role in both environmental and clinical settings. This adaptability may facilitate the transmission of antibiotic resistance and other virulence factors among different species, posing a significant challenge for public health and necessitating ongoing monitoring and research into its ecological impact and pathogenic mechanisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 95NR1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 95NR1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence.

Gene Summary

Adenine Count

22646 bp

Thymine Count

22762 bp

Guanine Count

20666 bp

Cytosine Count

20843 bp

Genome Length

86917 bp

Protein-coding Genes

5 genes

Non-Coding Genes

100 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glucuronide uptake porin uidcEC95NR1_RS10450Not AvailableNegative1946617 - 194788246680.3
glucuronide transporterEC95NR1_RS10455Not AvailableNegative1947921 - 194929449935.1
beta-glucuronidaseEC95NR1_RS10460Not AvailableNegative1949291 - 195110268464.6
dna-binding transcriptional regulator uidrEC95NR1_RS10465Not AvailableNegative1951491 - 195208121817.5
7-alpha-hydroxysteroid dehydrogenaseEC95NR1_RS10470Not AvailableNegative1952302 - 195306926780.2
mal regulon transcriptional regulator maliEC95NR1_RS10475Not AvailableNegative1953181 - 195420936626.9
pts maltose transporter subunit iicbEC95NR1_RS10480Not AvailablePositive1954384 - 195597656601.5
bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase malyEC95NR1_RS10485Not AvailablePositive1955986 - 195715843662.2
adenosine deaminaseEC95NR1_RS10490Not AvailablePositive1957262 - 195826336399.6
oxidoreductaseEC95NR1_RS10495Not AvailableNegative1958298 - 195933838244.5

Displaying genes 2811 – 2820 of 5812 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total